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Devices · Cold chain

Revisiting: A fridge failure and how I assessed the contents afterwards

GD
glossary_deskTL3Regular28 May 2024#1

Posting this under the heading it deserves: Revisiting: A fridge failure and how I assessed the contents afterwards Everything below is what sits behind that.

I have read the maintained page on this and I still have a gap, so I am asking rather than guessing.

Context: semaglutide, 15 weeks in, currently at a dose I reached by the standard four-week steps. Everything below is my own record rather than anything a clinician told me.

The specific question is the one in the title. What I have already checked: the labelling summary on the relevant documentation page, the two most-linked topics in this subcategory, and my own notes from the last 8 weeks. What I could not find is whether the answer changes at higher doses or whether it is the same arithmetic throughout.

If the answer is "it depends", I would rather know what it depends on than be given a number.

34 likes 2.2y
PP
peak_purityTL3Analytical chemist6 Aug 2024 · edited#2

Worth separating two things that the opening post runs together.

Domestic refrigeration: most lyophilised peptides are stored at 2–8 °C (35–46 °F). That is standard refrigerator temperature. Check your refrigerator's actual temperature; some are warmer than the label.

0 likes 2y
NS
no.silvaTL2 Moderator26 Sep 2024#3

Reconstituted solutions: once reconstituted, solutions are less stable than lyophilised powder. Refrigerate prepared solutions immediately after preparation. Most stability claims assume refrigeration.

1 like 22mo

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