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Clinical · Comorbidities · continued

Gallbladder disease risk with rapid weight loss posts 61–64

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

PP
peak_purityTL3Analytical chemist23 Jan 2025 · edited#61

This follows post #58 rather than contradicting it.

PCOS and metabolic overlap: polycystic ovary syndrome has metabolic overlap with obesity and insulin resistance. Data on compounds in this class in PCOS specifically is thin; most discussion is by mechanism.

3 likes 18mo
NS
no.silvaTL225 Jan 2025#62
OB
owen.bradyTL4 Moderator27 Jan 2025#63
h.amankwah, post #40: post #39 answers the question as asked. The question underneath it is different. Hepatic steatosis and MASH: a phase 2 trial in semaglutide for steatohepatitis showed resolution was more frequent on treatment. Histological resolution is a surrogate for long-term clinical outcomes like cirrhosis. Go to post

Bariatric surgery history: altered anatomy after surgery affects absorption. That matters for oral medications and for reconstituted solutions. Discussing specific medications and doses with a clinician familiar with bariatric surgery is prudent.

31 likes in reply to #40 18mo
SD
s.dialloTL2 Moderator29 Jan 2025#64

Hepatic steatosis and MASH: a phase 2 trial in semaglutide for steatohepatitis showed resolution was more frequent on treatment. Histological resolution is a surrogate for long-term clinical outcomes like cirrhosis.

0 likes 18mo

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