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Topic summary

Priming a pen and whether the primed volume is wasted

This is a generated summary. It shows the 5 most-liked posts from a topic of 24, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
AN
a.norgaardTL2 Moderator10 Jul 2026#1

Priming a pen and whether the primed volume is wasted Writing it up because I had to work it out twice and would rather nobody else did.

Practical question with the units stated, because I have seen how quickly these go wrong without them.

I have a 2 mg vial of tirzepatide and I am working to a 0.5 mg step. My syringes are U-100 insulin syringes, 0.3 mL barrel.

I can do the arithmetic and I have done it twice, getting the same answer both times, but I would like someone to check the reasoning rather than the number — specifically whether I have thought about the residual volume correctly, and whether the graduation I am landing on is one a person can actually read.

31 likes 18d
CH
ca.haddadTL2 Moderator Solution12 Jul 2026#3
g.haaland, post #2: the opening post answers the question as asked. The question underneath it is different. Pen confusion between compounds: if you are using multiple pens or alternating pens, confirming you have the correct pen before injection prevents administration errors. Check the label every time. Go to post
Community wiki post. Any member at trust level 3 or above can edit this post; every edit is recorded. Last edited by mira.patel on 25 Jul 2026.
  • 25 Jul 2026 — mira.patel: Replaced an unsourced figure with the published one and cited it.
Editors: mira.patel, customs_ledger, formulary_notes

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

7 likes in reply to #2 16d
FA
f.abrahamsenTL2Member13 Jul 2026#4

Dose counters: pens show the remaining number of doses. When the counter reaches zero, the pen is empty and cannot deliver more. Noting the counter before injection prevents running out unexpectedly.

32 likes 15d
NZ
n.zielinskiTL2 Moderator17 Jul 2026#9

On post #5 — agreed on the reasoning, with one qualification.

Priming: most pens require priming before the first use (injecting a small amount to fill the needle and line). Not priming can result in no dose being delivered on the first injection.

31 likes 11d
BR
buffer_reviewTL3Regular21 Jul 2026#16

Priming: most pens require priming before the first use (injecting a small amount to fill the needle and line). Not priming can result in no dose being delivered on the first injection.

27 likes 7d

Read the full topic (24 posts)

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