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Contains arithmetic shown step by step.

139 topics 42 solved Group: Status

Practice 47 Research Methods 26 Start Here 25 Data & Tools 14 Pharmacology 14 Devices 13

Related in this group: solved · open question · needs a source · long read · beginner friendly · data table · disputed

139 topics · page 1 of 5

Topic	Participants	Replies	Views	Activity
Reading a syringe in poor light, and how to avoid needing to Devices › Syringes & needles syringe units dead volume needle gauge & length worked example Solved Reading a syringe in poor light, and how to avoid needing to Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen…		2	22k	just now
How to ask a question when you cannot say why you are asking it Start Here › How to Ask beginner friendly site feedback worked example onboarding Solved Asking directly, because I could not find a straight answer: How to ask a question when you cannot say why you are asking it Question in the title. Context below, and I have tried to include the things people…	+49	53	36k	4h
[2026 update] Correlation in a self-tracked dataset: what it can support Research Methods › Statistics number needed to treat effect size worked example heterogeneity Posting this under the heading it deserves: Correlation in a self-tracked dataset: what it can support Everything below is what sits behind that. I have seen SURMOUNT-4 ( JAMA , 2024) cited in support of a…		2	31k	6h
The anatomy of a question that gets answered within an hour Start Here › How to Ask worked example site feedback onboarding beginner friendly Wiki The anatomy of a question that gets answered within an hour — setting out what I have, and where I think it stops being reliable. Question in the title. Context below, and I have tried to include the things…	+113	127	2.7k	13h
Rewriting my first post: a before-and-after, with commentary — what changed since Start Here › How to Ask site feedback onboarding beginner friendly worked example Posting this under the heading it deserves: Rewriting my first post: a before-and-after, with commentary — what changed since Everything below is what sits behind that. I want to check my reasoning rather…	+15	19	12k	13h
About the N-of-1 designs category Research Methods › N-of-1 designs worked example confounding effect size Pinned Wiki Designing a personal experiment that could actually change your mind, including washouts and blinding. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is…		4	22k	14h
Restarting after a long gap: what the labelling implies Practice › Dosing & titration dose reduction semaglutide titration missed dose Posting this under the heading it deserves: Restarting after a long gap: what the labelling implies Everything below is what sits behind that. I have read the maintained page on this and I still have a gap,…	+41	46	11k	15h
Second pass at: Absence of evidence and evidence of absence Research Methods › Statistics worked example confounding number needed to treat On the subject in the title: Second pass at: Absence of evidence and evidence of absence Working notes rather than a conclusion. Session topic: SELECT ( N Engl J Med , 2023). Please read it before posting;…	+50	55	18k	16h
A 10 mg vial reconstituted three different ways, compared Practice › Reconstitution bacteriostatic water worked example concentration maths Posting this under the heading it deserves: A 10 mg vial reconstituted three different ways, compared Everything below is what sits behind that. Practical question with the units stated, because I have seen…	+30	34	55k	17h
A calculator that gives a right answer to the wrong question Data & Tools › Calculators concentration maths worked example site feedback syringe units Posting this under the heading it deserves: A calculator that gives a right answer to the wrong question Everything below is what sits behind that. I would like to understand what this number means before I…	+32	36	1.9k	17h
When a dose reduction is the correct response to a side effect Practice › Dosing & titration dose reduction tirzepatide titration missed dose Solved When a dose reduction is the correct response to a side effect — that is the question, and I have not found it answered plainly anywhere I have looked. A question about technique rather than about dose. I…	+38	42	2.7k	19h
Blinding yourself: practical methods and their limits — the long version Research Methods › N-of-1 designs worked example effect size confounding data table Blinding yourself: practical methods and their limits — the long version Writing it up because I had to work it out twice and would rather nobody else did. I have seen SURMOUNT-OSA ( N Engl J Med , 2024)…	+7	11	1.8k	22h
Reading U-100 graduations, with a conversion table Devices › Syringes & needles dead volume worked example subcutaneous injection needle gauge & length Posting this under the heading it deserves: Reading U-100 graduations, with a conversion table Everything below is what sits behind that. Practical question with the units stated, because I have seen how…	+35	41	2k	1d
Coming back to: Why I now write the concentration on the vial in marker Practice › Reconstitution reconstitution syringe units bacteriostatic water worked example The question in the title: Why I now write the concentration on the vial in marker I will give what I have already checked below so nobody repeats it. Practical question with the units stated, because I have…	+8	12	4.3k	1d
Asking a follow-up: new topic or new reply? Start Here › How to Ask worked example onboarding beginner friendly Solved Asking a follow-up: new topic or new reply? — that is the question, and I have not found it answered plainly anywhere I have looked. Question in the title. Context below, and I have tried to include the…	+68	73	40k	1d
Coming back to: Where the four-week escalation interval comes from, and what it is not Practice › Dosing & titration dose reduction semaglutide titration tirzepatide Solved Posting this under the heading it deserves: Where the four-week escalation interval comes from, and what it is not Everything below is what sits behind that. I have read the maintained page on this and I…	+44	48	11k	1d
How much of the diluent volume the powder itself displaces Practice › Reconstitution concentration maths bacteriostatic water dead volume worked example Asking directly, because I could not find a straight answer: How much of the diluent volume the powder itself displaces Practical question with the units stated, because I have seen how quickly these go wrong…		2	1.8k	1d
Washout with a one-week half-life: the arithmetic — does this still hold? Research Methods › N-of-1 designs confounding data table worked example Solved Washout with a one-week half-life: the arithmetic — does this still hold? — that is the question, and I have not found it answered plainly anywhere I have looked. Comparing SURPASS-2 ( N Engl J Med , 2021)…	+41	45	12k	1d
Peak-to-trough ratio at steady state for a weekly agent — the long version Pharmacology › Pharmacokinetics semaglutide missed dose tirzepatide worked example Under review Peak-to-trough ratio at steady state for a weekly agent — the long version Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means…	+57	61	708	1d
Coming back to: How much context is too much context in a first post? Start Here › How to Ask beginner friendly site feedback worked example onboarding Asking directly, because I could not find a straight answer: How much context is too much context in a first post? Question in the title. Context below, and I have tried to include the things people here…	+2	6	7.5k	1d
A 5 mg vial and a 0.25 mg dose: the arithmetic in full Practice › Reconstitution syringe units worked example reconstitution bacteriostatic water Solved A 5 mg vial and a 0.25 mg dose: the arithmetic in full Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated, because I have seen how…	+124	141	16k	2d
Micro-titration: a disputed topic, argued properly Practice › Dosing & titration titration dose reduction worked example tirzepatide Solved Wiki Micro-titration: a disputed topic, argued properly Writing it up because I had to work it out twice and would rather nobody else did. A question about technique rather than about dose. I have been doing the…	+99	110	61k	2d
Coming back to: Time to steady state after a dose increase Pharmacology › Pharmacokinetics semaglutide missed dose liraglutide worked example Time to steady state after a dose increase Writing it up because I had to work it out twice and would rather nobody else did. Posting the method first, because I know what the first three replies will…	+104	110	16k	2d
Stepping down deliberately, and how to do it without losing progress — what changed since Practice › Dosing & titration tirzepatide semaglutide titration missed dose Under review Posting this under the heading it deserves: Stepping down deliberately, and how to do it without losing progress — what changed since Everything below is what sits behind that. Practical question with the…	+94	99	29k	2d
Designing a personal experiment that could change your mind — one year on Research Methods › N-of-1 designs effect size data table worked example Designing a personal experiment that could change your mind — one year on — setting out what I have, and where I think it stops being reliable. Session topic: STEP 4 ( JAMA , 2021). Please read it before…	+74	80	17k	2d
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Devices › Syringes & needles syringe units subcutaneous injection needle gauge & length dead volume Wiki 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters — setting out what I have, and where I think it stops being reliable. Practical question with the units stated, because I have seen how quickly…	+104	114	6k	6d
Why we ask for units every single time, with three examples of what goes wrong Start Here › How to Ask worked example onboarding beginner friendly guidelines Why we ask for units every single time, with three examples of what goes wrong — that is the question, and I have not found it answered plainly anywhere I have looked. Question in the title. Context below,…	+118	135	2.2k	11d
What to include when your question involves a chromatogram — one year on Start Here › How to Ask worked example guidelines site feedback onboarding Asking directly, because I could not find a straight answer: What to include when your question involves a chromatogram — one year on Question in the title. Context below, and I have tried to include the…	+69	75	862	14d
How much context is too much context in a first post? Start Here › How to Ask guidelines beginner friendly onboarding site feedback Solved How much context is too much context in a first post? I have a specific reason for asking rather than idle curiosity, and the context is below. Question in the title. Context below, and I have tried to…	+70	74	935	18d
Second pass at: The storage lookup and where its data comes from Data & Tools › Calculators concentration maths syringe units site feedback worked example On the subject in the title: Second pass at: The storage lookup and where its data comes from Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a…	+38	42	13k	19d

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