Tags · Compound
liraglutide
Daily GLP-1 receptor agonist; the older comparator in much of the literature.
Related in this group: semaglutide · tirzepatide · retatrutide · cagrilintide · cagrisema · dulaglutide · exenatide · orforglipron · oral semaglutide · survodutide · mazdutide · amylin analogues
12 topics
| Topic | Participants | Replies | Views | Activity |
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Peak-to-trough ratio at steady state for a weekly agent — the long version
Peak-to-trough ratio at steady state for a weekly agent — the long version Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means…
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+57 | 61 | 708 | 1d |
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Coming back to: Time to steady state after a dose increase
Time to steady state after a dose increase Writing it up because I had to work it out twice and would rather nobody else did. Posting the method first, because I know what the first three replies will…
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+104 | 110 | 16k | 2d |
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Peak-to-trough ratio at steady state for a weekly agent
On the subject in the title: Peak-to-trough ratio at steady state for a weekly agent Working notes rather than a conclusion. I would like to understand what this number means before I repeat it anywhere. A…
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+58 | 64 | 9.7k | 2mo |
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Clearance pathways and what renal impairment changes
Clearance pathways and what renal impairment changes Writing it up because I had to work it out twice and would rather nobody else did. I would like to understand what this number means before I repeat it…
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+11 | 15 | 43k | 2mo |
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Coming back to: Half-life, steady state, and accumulation worked through
On the subject in the title: Half-life, steady state, and accumulation worked through Working notes rather than a conclusion. Working through the identity arithmetic and I would like it checked. semaglutide…
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+14 | 18 | 15k | 3mo |
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Half-life, steady state, and accumulation worked through — a second dataset
Half-life, steady state, and accumulation worked through — a second dataset — setting out what I have, and where I think it stops being reliable. Working through the identity arithmetic and I would like it…
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+110 | 126 | 14k | 4mo |
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About the Pharmacokinetics category
Half-life, accumulation, steady state, albumin binding, and why weekly dosing works. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author…
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4 | 32k | 8mo | |
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Follow-up: Subcutaneous absorption kinetics and site differences
Subcutaneous absorption kinetics and site differences — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I repeat it anywhere. A…
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4 | 9.9k | 10mo | |
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[2026 update] Clearance pathways and what renal impairment changes
On the subject in the title: Clearance pathways and what renal impairment changes Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in front…
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+63 | 69 | 50k | 13mo |
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Half-life, steady state, and accumulation worked through
Half-life, steady state, and accumulation worked through Writing it up because I had to work it out twice and would rather nobody else did. Working through the identity arithmetic and I would like it checked.…
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+115 | 130 | 44k | 13mo |
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Albumin binding and how it produces a long half-life
Albumin binding and how it produces a long half-life — setting out what I have, and where I think it stops being reliable. I would like to understand what this number means before I repeat it anywhere. A…
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+38 | 44 | 6.6k | 14mo |
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Time to steady state after a dose increase
On the subject in the title: Time to steady state after a dose increase Working notes rather than a conclusion. A documentation question rather than an analytical one. I have a certificate in front of me that…
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+151 | 163 | 9.7k | 21mo |