Worth separating two things that post #117 runs together.
Freeze-thaw: some peptides tolerate freezing; others do not. Check your compound's labelling. Generally, repeated freeze-thaw is worse than single freeze-thaw.
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
Worth separating two things that post #117 runs together.
Freeze-thaw: some peptides tolerate freezing; others do not. Check your compound's labelling. Generally, repeated freeze-thaw is worse than single freeze-thaw.
Assessing an excursion: if a package sat at room temperature for a time, visual inspection (cloudiness, discoloration, particles) can alert you to problems. Not visible does not mean not damaged, but visible problems are a reason to contact the supplier.
Domestic refrigeration: most lyophilised peptides are stored at 2–8 °C (35–46 °F). That is standard refrigerator temperature. Check your refrigerator's actual temperature; some are warmer than the label.
This follows post #121 rather than contradicting it.
Shipping container and cold packs: reputable suppliers use insulated containers with cold packs designed to arrive cool. Checking on arrival that cold packs are still cold is a sign the chain was maintained.
On post #121 — agreed on the reasoning, with one qualification.
Shipment during summer or to hot climates: consider shipping to a cold-storage facility rather than to home if temperatures will be high. Alternatively, time shipment to arrive when you can refrigerate immediately.
post #125 answers the question as asked. The question underneath it is different.
Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.
Assessing an excursion: if a package sat at room temperature for a time, visual inspection (cloudiness, discoloration, particles) can alert you to problems. Not visible does not mean not damaged, but visible problems are a reason to contact the supplier.
Temperature logging: devices that record temperature over time let you confirm cold chain was maintained. Useful if a shipment was delayed or if you are concerned about excursion.
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Domestic fridge temperature mapping: a cheap experiment
Domestic fridge temperature mapping: a cheap experiment Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I still have a gap, so I…
|
2 | 182 | 14mo | |
|
A fridge failure and how I assessed the contents afterwards
A fridge failure and how I assessed the contents afterwards Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I still have a gap,…
|
+14 | 18 | 46k | 17h |
|
Domestic fridge temperature mapping: a cheap experiment — what changed since
Domestic fridge temperature mapping: a cheap experiment — what changed since — setting out what I have, and where I think it stops being reliable. I have read the maintained page on this and I still have a…
|
+145 | 155 | 46k | 12mo |
|
Revisiting: A fridge failure and how I assessed the contents afterwards
Posting this under the heading it deserves: Revisiting: A fridge failure and how I assessed the contents afterwards Everything below is what sits behind that. I have read the maintained page on this and I…
|
2 | 15k | 22mo | |
|
Temperature loggers worth the money
Temperature loggers worth the money — setting out what I have, and where I think it stops being reliable. Reporting something rather than asking about it, in case the pattern is useful to anyone else. Over 10…
|
+46 | 50 | 8k | 9mo |
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Revisiting: A fridge failure and how I assessed the contents afterwards
Posting this under the heading it deserves: Revisiting: A fridge failure and how I assessed the contents afterwards Everything below is what sits behind that. I have read the maintained page on this and I…
|
2 | 15k | 22mo | |
|
What published stability data actually covers, and what it does not
Asking directly, because I could not find a straight answer: What published stability data actually covers, and what it does not Reporting something rather than asking about it, in case the pattern is useful…
|
+8 | 12 | 435 | 1d |
|
Second pass at: Adsorptive losses at low concentration, and why dilute solutions are fragile
On the subject in the title: Second pass at: Adsorptive losses at low concentration, and why dilute solutions are fragile Working notes rather than a conclusion. Practical question with the units stated,…
|
+77 | 87 | 58k | 4mo |
|
About the Cold chain category
Domestic refrigeration, travel, temperature logging, and assessing an excursion after the fact. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with…
|
4 | 2k | 17mo | |
|
Freeze-thaw and why one cycle is not the same as five
On the subject in the title: Freeze-thaw and why one cycle is not the same as five Working notes rather than a conclusion. I have read the maintained page on this and I still have a gap, so I am asking rather…
|
+21 | 25 | 41k | 8mo |