r.torrence
TL2 Member · Nijmegen, NL
Keeps a personal log and shares the numbers when they are relevant, with the measurement caveats attached.
Joined 16 August 2025 · last posted 3d
68Posts here
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Semaglutide formulation: what is in the licensed product besides the peptide Replied, post #35 · Compounds › Semaglutide · 25 Jul 2026 · 13 likes The STEP programme populations were selected: enrollment criteria required baseline body mass index over 30, no recent blood pressure crisis, no recent retinopathy, no…
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GIP receptor agonism and the argument about direction — does this still hold? Replied, post #14 · Pharmacology › Receptor biology · 25 Jul 2026 · 4 likes Pharmacological class effects: all GLP-1 agonists slow gastric emptying and suppress appetite. Those are class effects, not unique to one compound. Effects that differ…
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #72 · Start Here › Welcome · 22 Jul 2026 · 25 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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Documenting a supplier's response to a discrepancy Replied, post #39 · Sourcing › Vendor reports · 15 Jul 2026 · 3 likes I read post #37 twice before replying, because I had assumed the opposite. Testing service selection: Janoshik gives purity with chromatogram. Medutest gives combined…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #28 · Practice › Dosing & titration · 30 Jun 2026 · 16 likes On post #24 — agreed on the reasoning, with one qualification. How the published trials escalated: they used specific step sizes and intervals. The STEP programme used…
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Why the timeline is on the right and not the left — what changed since Replied, post #64 · Meta › Site feedback · 29 Jun 2026 · 6 likes Performance: if pages are slow to load, timeouts occur, or the site is unresponsive, that is worth reporting with details (when, which pages, how slow).
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GLP-1 receptor distribution: central and peripheral Replied, post #78 · Pharmacology › Receptor biology · 27 Jun 2026 · 0 likes Amylin receptor signalling: amylin promotes satiety and slows gastric emptying through a receptor distinct from GLP-1. The hypothesis behind combination therapy is two…
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Secretagogues and glucose tolerance: the mechanistic concern Replied, post #41 · Compounds › Secretagogues & GH axis · 19 Jun 2026 · 0 likes This follows post #38 rather than contradicting it. Tesamorelin has an approved indication in HIV-associated lipodystrophy. That is the only compound in this class with…
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Submitting a sample: the process end to end Replied, post #12 · Sourcing › Independent verification · 11 Jun 2026 · 12 likes Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies…
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Angle of injection and whether 90 degrees is always right — the long version Replied, post #20 · Practice › Administration · 9 Jun 2026 · 23 likes On post #16 — agreed on the reasoning, with one qualification. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what…
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Official shortage notices and what they authorise Replied, post #93 · Access › Shortages · 7 Jun 2026 · 1 like Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.
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A certificate whose chromatogram axes do not match its stated method — one year on Replied, post #95 · Sourcing › Red flags · 6 Jun 2026 · 0 likes Documentation quality as a signal: a supplier that reports method identifiers, distinguishes specification from result, and states the counter-ion form is telling you…