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Devices · Syringes & needles

A ten-fold dose error caught before injection — one year on

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IsaksenTL3Regular31 Jul 2025#1

On the subject in the title: A ten-fold dose error caught before injection — one year on Working notes rather than a conclusion.

A question about technique rather than about dose.

I have been doing the same thing for 5 months and it works, and then I read one of the documentation pages here and realised I may have been reasoning from a misunderstanding the whole time. Nothing has gone wrong; I would just like to understand why it has not.

What I do, exactly, is described below. Please tell me which parts are load-bearing and which are superstition.

4 likes 12mo
KO
k.okaforTL2 Moderator31 Jul 2025#2

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

8 likes 12mo
L
LeitermanTL3Regular31 Jul 2025#3
Isaksen, post #1: On the subject in the title: A ten-fold dose error caught before injection — one year on Working notes rather than a conclusion. A question about technique rather than about dose. I have been doing the same thing for 5 months and it works, and then I read one of the documentation pages here and realised I may have been reasoning from a… Go to post

post #2 is right about the mechanism and I think understates the practical bit.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

19 likes in reply to #1 12mo
GE
g.ekstromTL2 Moderator31 Jul 2025 · edited#4
k.okafor, post #2: Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity. Go to post

Worth separating two things that post #3 runs together.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

0 likes in reply to #2 12mo
AR
ambient_reviewTL3Regular31 Jul 2025#5

Picking up post #2: that is the part I would want checked first.

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

4 likes 12mo
PO
pe.onwukaTL2 Moderator31 Jul 2025#6

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

12 likes 12mo
JH
j.habermannTL3Regular31 Jul 2025#7
Isaksen, post #1: On the subject in the title: A ten-fold dose error caught before injection — one year on Working notes rather than a conclusion. A question about technique rather than about dose. I have been doing the same thing for 5 months and it works, and then I read one of the documentation pages here and realised I may have been reasoning from a… Go to post

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

26 likes in reply to #1 12mo
NS
ni.stanescuTL21 Aug 2025#8
DN
desiccant_notesTL2Member1 Aug 2025#9

This follows post #6 rather than contradicting it.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

7 likes 12mo
SR
s.roosTL2 Moderator1 Aug 2025#10
j.habermann, post #7: Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error. Go to post

I read post #8 twice before replying, because I had assumed the opposite.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

18 likes in reply to #7 12mo
FR
f.rasmussenTL2 Moderator1 Aug 2025#11
ambient_review, post #5: Picking up post #2: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

Worth separating two things that post #7 runs together.

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

0 likes in reply to #5 12mo
MD
m.dalgaardTL3Regular1 Aug 2025#12

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

23 likes 12mo
EA
e.adeyemiTL2 Moderator1 Aug 2025#13

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

6 likes 12mo
PR
policy_readerTL2Regular1 Aug 2025#14

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

1 like 12mo
MM
m.mwangiTL2 Moderator1 Aug 2025#15
ni.stanescu, post #8: On post #4 — agreed on the reasoning, with one qualification. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive. Go to post

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

32 likes in reply to #8 12mo
GT
g.tanakaTL3Regular1 Aug 2025#16
ambient_review, post #5: Picking up post #2: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

17 likes in reply to #5 12mo
MI
m.ilungaTL2 Moderator1 Aug 2025 · edited#17

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

3 likes 12mo
DS
d.szymanskiTL3Wiki editor1 Aug 2025#18

Picking up post #15: that is the part I would want checked first.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

0 likes 12mo
ST
s.teixeiraTL21 Aug 2025#19
K
KAnderssonTL3Regular1 Aug 2025#20

post #19 is right about the mechanism and I think understates the practical bit.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

0 likes 12mo
NG
np_gilmoreTL3Nurse practitioner1 Aug 2025#21
j.habermann, post #7: Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error. Go to post

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

1 like in reply to #7 12mo
MV
m.vukovicTL2 Moderator1 Aug 2025#22
m.dalgaard, post #12: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

On post #18 — agreed on the reasoning, with one qualification.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

5 likes in reply to #12 12mo
SC
sourced_claimsTL3Regular1 Aug 2025#23

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

15 likes 12mo
RZ
ro.zielinskiTL2 Moderator1 Aug 2025#24

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

30 likes 12mo
PN
priorauth_notesTL2Regular1 Aug 2025 · edited#25

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

2 likes 12mo
MK
m.kjaerTL2 Moderator1 Aug 2025#26
m.dalgaard, post #12: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

9 likes in reply to #12 12mo
M
microgramsTL2Regular1 Aug 2025#27

This follows post #24 rather than contradicting it.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

21 likes 12mo
EM
e.mbekiTL2 Moderator1 Aug 2025#28

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

0 likes 12mo
SB
s.bruunTL2 Moderator1 Aug 2025#29
m.mwangi, post #15: Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose. Go to post

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

5 likes in reply to #15 12mo
GR
g.rasmussenTL2 Moderator1 Aug 2025#30

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

14 likes 12mo