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Devices · Syringes & needles · continued

A ten-fold dose error caught before injection posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

NV
n.villalobosTL2 Moderator8 May 2025 · edited#31
e.roos, post #26: Picking up post #23: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

post #30 answers the question as asked. The question underneath it is different.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

9 likes in reply to #26 15mo
FP
forest_plotTL3Evidence synthesis10 May 2025#32

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

20 likes 15mo
SA
s.antonsenTL2 Moderator12 May 2025#33

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

0 likes 15mo
QZ
q.zhao_qaTL3Quality assurance14 May 2025#34

Coming back to post #32, because the follow-up matters more than the original answer.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

2 likes 14mo
CO
c.ostergaardTL2 Moderator16 May 2025#35
e.roos, post #26: Picking up post #23: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

post #34 is right about the mechanism and I think understates the practical bit.

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

14 likes in reply to #26 14mo
PI
p.iyer_pharmdTL318 May 2025#36
HI
h.iyerTL2 Moderator21 May 2025#37

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

0 likes 14mo
BI
blank_injectionTL2Analytical chemist23 May 2025#38

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

5 likes 14mo
BD
b.dumitruTL2 Moderator25 May 2025#39

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

20 likes 14mo
NT
nl_translatorTL2Translator · NL27 May 2025#40

On post #36 — agreed on the reasoning, with one qualification.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

0 likes 14mo
MS
m.stephanopoulosTL3Regular29 May 2025#41
Lundqvist, post #19: Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose. Go to post

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

15 likes in reply to #19 14mo
BN
b.nwosuTL2 Moderator31 May 2025#42

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

5 likes 14mo
RG
r.girardTL2 Moderator2 Jun 2025#43

Coming back to post #41, because the follow-up matters more than the original answer.

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

1 like 14mo
ZI
z.iyerTL2 Moderator4 Jun 2025#44

Picking up post #41: that is the part I would want checked first.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

0 likes 14mo
AZ
a.zamoraTL2 Moderator6 Jun 2025 · edited#45
t.pereira, post #17: Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

10 likes in reply to #17 14mo
CS
c.silvaTL2 Moderator8 Jun 2025#46
h.jansen, post #7: On post #3 — agreed on the reasoning, with one qualification. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had been repeating something I had not checked carefully enough. Go to post

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

3 likes in reply to #7 14mo
BF
b.fonsecaTL2 Moderator10 Jun 2025#47

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

0 likes 14mo
DT
d.tammTL2 Moderator12 Jun 2025#48

This follows post #45 rather than contradicting it.

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

30 likes 14mo
AN
a.novakTL2 Moderator14 Jun 2025#49
s.antonsen, post #33: For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use. Go to post

On post #45 — agreed on the reasoning, with one qualification.

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

29 likes in reply to #33 13mo
AA
a.adebayoTL2 Moderator16 Jun 2025#50
e.dalgleish, post #23: Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had been repeating something I had not checked carefully enough. Go to post

post #49 answers the question as asked. The question underneath it is different.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

14 likes in reply to #23 13mo
MS
m.steinerTL2 Moderator18 Jun 2025 · edited#51
il.dumitru, post #30: Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less. Go to post

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

23 likes in reply to #30 13mo
FD
f.demirTL2Regular20 Jun 2025#52

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

0 likes 13mo
JM
j.moreauTL2 Moderator22 Jun 2025#53

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

1 like 13mo
BV
bias_varianceTL4Biostatistician24 Jun 2025#54
f.laurent, post #20: I read post #18 twice before replying, because I had assumed the opposite. Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters. Go to post

On post #50 — agreed on the reasoning, with one qualification.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

6 likes in reply to #20 13mo
HD
h.delgadoTL2 Moderator26 Jun 2025#55
blank_injection, post #38: Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers. Go to post

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

16 likes in reply to #38 13mo
IT
impurity_tableTL3Analytical chemist28 Jun 2025#56

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

32 likes 13mo
NL
n.laurentTL2 Moderator30 Jun 2025#57

post #56 is right about the mechanism and I think understates the practical bit.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

0 likes 13mo
CR
compounding_ruthTL4Pharmacist2 Jul 2025#58

Worth separating two things that post #54 runs together.

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

3 likes 13mo
VB
va.baptistaTL2 Moderator3 Jul 2025#59

Picking up post #56: that is the part I would want checked first.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

0 likes 13mo
TV
t.vasquezTL4 Moderator5 Jul 2025#60
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

Coming back to post #58, because the follow-up matters more than the original answer.

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

1 like 13mo