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Evidence · Preprints

Citing a preprint in a maintained document: our rule and its reasoning — does this still hold?

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Solved by n.kravchenko in post #6
This follows post #3 rather than contradicting it. Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

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C
CFairweatherTL1Member24 Sep 2025#1

The question in the title: Citing a preprint in a maintained document: our rule and its reasoning — does this still hold? I will give what I have already checked below so nobody repeats it.

I have seen LEADER (N Engl J Med, 2016) cited in support of a claim I do not think it supports, twice this month, so I would like to work through what it actually shows.

My reading is that the trial is sound for its own question and is being stretched to answer a different one. I might be wrong about that, which is why this is a topic rather than a correction.

What I would like from this discussion: someone who disagrees with me to say why, with the section of the paper they are relying on.

28 likes 10mo
RF
ro.friskTL2 Moderator24 Sep 2025#2

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

5 likes 10mo
DS
dr_seongTL3Physician25 Sep 2025#3
CFairweather, post #1: The question in the title: Citing a preprint in a maintained document: our rule and its reasoning — does this still hold? I will give what I have already checked below so nobody repeats it. I have seen LEADER ( N Engl J Med , 2016) cited in support of a claim I do not think it supports, twice this month, so I would like to work through… Go to post

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

1 like in reply to #1 10mo
IA
i.almeidaTL2 Moderator25 Sep 2025#4

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

0 likes 10mo
ST
slow_titratorTL2Regular25 Sep 2025#5

I read post #3 twice before replying, because I had assumed the opposite.

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

10 likes 10mo
NK
n.kravchenkoTL2 Moderator Solution25 Sep 2025#6

This follows post #3 rather than contradicting it.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

10 likes 10mo
WN
w.novakTL3Regular25 Sep 2025#7

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes 10mo
FW
f.weissTL225 Sep 2025#8
DO
dr_okonkwoTL4 Moderator25 Sep 2025#9
n.kravchenko, post #6: This follows post #3 rather than contradicting it. Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

29 likes in reply to #6 10mo
FS
f.sjobergTL2 Moderator25 Sep 2025#10
i.almeida, post #4: Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions. Go to post

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

14 likes in reply to #4 10mo
JF
j.falkTL2 Moderator26 Sep 2025#11

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

0 likes 10mo
BJ
b.jankowiakTL3Regular26 Sep 2025#12

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

5 likes 10mo
HE
h.espinozaTL2 Moderator26 Sep 2025#13
f.weiss, post #8: Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting. Go to post

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

14 likes in reply to #8 10mo
YM
y.mensahTL3Wiki editor26 Sep 2025#14

On post #10 — agreed on the reasoning, with one qualification.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

29 likes 10mo
NK
n.kravchenkoTL2 Moderator26 Sep 2025#15

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

0 likes 10mo
ST
slow_titratorTL2Regular26 Sep 2025#16

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

2 likes 10mo
FW
f.weissTL2 Moderator26 Sep 2025#17
b.jankowiak, post #12: Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised. Go to post

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

9 likes in reply to #12 10mo
WN
w.novakTL3Regular26 Sep 2025 · edited#18

Worth separating two things that post #14 runs together.

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

21 likes 10mo
RF
ro.friskTL2 Moderator26 Sep 2025 · edited#19

Picking up post #16: that is the part I would want checked first.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

0 likes 10mo
CL
customs_ledgerTL3Regular27 Sep 2025#20

Coming back to post #18, because the follow-up matters more than the original answer.

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

1 like 10mo
SK
s.kimaniTL2 Moderator27 Sep 2025#21

Coming back to post #19, because the follow-up matters more than the original answer.

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

0 likes 10mo
NH
n.haddadTL2 Moderator27 Sep 2025#22
customs_ledger, post #20: Coming back to post #18, because the follow-up matters more than the original answer. Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

0 likes in reply to #20 10mo
NS
n.stanescuTL2 Moderator27 Sep 2025#23

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

13 likes 10mo
JN
j.nwosuTL2 Moderator27 Sep 2025#24

post #23 answers the question as asked. The question underneath it is different.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

4 likes 10mo
BV
b.vanheckeTL2 Moderator27 Sep 2025#25

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

2 likes 10mo
MS
m.strand_rphTL3Pharmacist27 Sep 2025 · edited#26
CFairweather, post #1: The question in the title: Citing a preprint in a maintained document: our rule and its reasoning — does this still hold? I will give what I have already checked below so nobody repeats it. I have seen LEADER ( N Engl J Med , 2016) cited in support of a claim I do not think it supports, twice this month, so I would like to work through… Go to post

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

0 likes in reply to #1 10mo
DE
d.eriksenTL2 Moderator27 Sep 2025#27
s.kimani, post #21: Coming back to post #19, because the follow-up matters more than the original answer. Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real. Go to post

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

18 likes in reply to #21 10mo
JM
j.mwangiTL4 Moderator27 Sep 2025#28
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

post #27 is right about the mechanism and I think understates the practical bit.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

8 likes 10mo
G
GDashwoodTL3Regular27 Sep 2025#29

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

4 likes 10mo
CH
ca.haddadTL2 Moderator28 Sep 2025#30

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

0 likes 10mo