Compounds · Secretagogues & GH axis · continued

CJC-1295 with and without DAC: what the modification does posts 121–124

Compounds › Secretagogues & GH axis needs a source tesamorelin CJC-1295 GHRP class

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

lyophil_marginTL3Regular24 Jul 2026#121

Evidence quality in the secretagogue literature is honestly weaker than in the incretin literature. Large randomised controlled trials are rare. Most evidence is mechanistic or from small studies. This is why this subcategory has higher sourcing standards than most.

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a.amankwahTL2 Moderator25 Jul 2026#122

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

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k.farrugiaTL3Regular26 Jul 2026#123

I read post #121 twice before replying, because I had assumed the opposite.

Why this subcategory is stricter about sourcing than most: the evidence base is weaker and that is precisely why documentation quality matters more. A supplier page that clearly identifies the compound and the purity is more valuable for secretagogues than for incretin agonists where the evidence base is stronger.

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m.yildizTL227 Jul 2026#124

Collapsed as off-topic by two members at trust level 3 or above

This follows post #121 rather than contradicting it.

Secretagogues and glucose tolerance: there is a mechanistic concern that sustained growth hormone elevation might impair glucose tolerance. The clinical relevance of this concern in practice is not well established.

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