Topic summary

Follow-up: History of disordered eating and why it changes the conversation

Clinical › Special populations bariatric surgery history older adults pregnancy & planning chronic kidney disease

This is a generated summary. It shows the 9 most-liked posts from a topic of 82, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.

a.iyerTL2 Moderator29 Apr 2025#3

l.wikstrom, post #1: Posting this under the heading it deserves: History of disordered eating and why it changes the conversation Everything below is what sits behind that. General question, not a request for advice about my own care — I know the difference and I would rather be told to see my prescriber than get an answer that pretends otherwise. I have a… Go to post

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

32 likes in reply to #1 15mo

GSwinburneTL1Member26 May 2025#14

post #13 answers the question as asked. The question underneath it is different.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

28 likes 14mo

MJayawardenaTL3Regular30 May 2025#16

This follows post #13 rather than contradicting it.

Pregnancy and planning: these compounds are not approved for use in pregnancy. Planning windows (how long to wait before attempting pregnancy) are not formally established. Conservative approaches wait several months to allow clearance.

29 likes 14mo

s.hartmannTL2 Moderator21 Jun 2025#27

post #26 is right about the mechanism and I think understates the practical bit.

Renal impairment: the compounds are cleared renally to some degree. Dose adjustments might be needed in severe renal impairment. Consulting with a clinician familiar with renal dosing is prudent.

29 likes 13mo

n.kuuselaTL2 Moderator26 Jun 2025#30

Gastroparesis: pre-existing severe delayed gastric emptying can worsen with compounds that slow it further. Discussion with a clinician is prudent if this history exists.

28 likes 13mo

v.bruunTL2 Moderator18 Jul 2025#43

r.mcalister, post #4: Coming back to the opening post, because the follow-up matters more than the original answer. Hepatic impairment: less is known about dosing in significant liver disease than in kidney disease. Extreme caution applies because the liver metabolises a large fraction of many medications. Go to post

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

33 likes in reply to #4 12mo

forest_plotTL3Evidence synthesis30 Jul 2025#50

a.iyer, post #3: I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient. Go to post

Hypoglycemia risk: in people already on insulin or sulfonylureas, adding a GLP-1 agonist requires insulin dose reduction and close monitoring for hypoglycemia. This is manageable with attention.

31 likes in reply to #3 12mo

c.marchettiTL2 Moderator3 Aug 2025#53

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

31 likes 12mo

taper_fileTL3Regular28 Aug 2025#69

29 likes 11mo

Read the full topic (82 posts)

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