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Topic summary

Hepatic impairment and the absence of data

This is a generated summary. It shows the 5 most-liked posts from a topic of 36, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
AW
a.westergaardTL3Regular30 Jul 2025#4

post #2 answers the question as asked. The question underneath it is different.

Pregnancy and planning: these compounds are not approved for use in pregnancy. Planning windows (how long to wait before attempting pregnancy) are not formally established. Conservative approaches wait several months to allow clearance.

28 likes 12mo
RI
retention_indexTL2Analytical chemist14 Aug 2025#12

Coming back to post #10, because the follow-up matters more than the original answer.

Pancreatitis history: the compounds can rarely trigger pancreatitis. A history of pancreatitis makes monitoring for recurrence more important during titration.

29 likes 11mo
AD
a.delgadoTL2 Moderator24 Aug 2025#19

Picking up post #16: that is the part I would want checked first.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

28 likes 11mo
ZL
z.laurentTL2 Moderator2 Sep 2025#25
c.ramos, post #15: This follows post #12 rather than contradicting it. Pregnancy and planning: these compounds are not approved for use in pregnancy. Planning windows (how long to wait before attempting pregnancy) are not formally established. Conservative approaches wait several months to allow clearance. Go to post

Pancreatitis history: the compounds can rarely trigger pancreatitis. A history of pancreatitis makes monitoring for recurrence more important during titration.

29 likes in reply to #15 11mo
SG
s.grahameTL2Member13 Sep 2025#33

Pregnancy and planning: these compounds are not approved for use in pregnancy. Planning windows (how long to wait before attempting pregnancy) are not formally established. Conservative approaches wait several months to allow clearance.

24 likes 10mo

Read the full topic (36 posts)

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