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Evidence · Journal club · continued

Second pass at: Journal club: STEP 4 and what a withdrawal design can prove posts 91–91

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

KC
k.chukwuTL2 Moderator11 Nov 2025#91

SURMOUNT-OSA (N Engl J Med 2024): Tirzepatide in obstructive sleep apnoea, using an objective physiological endpoint. Notable because soft endpoints are avoided. Two parallel trials addressed the confounder directly.

17 likes 9mo

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