Topic summary

"Should I double up?" — answered once, at length, calmly

Practice › Administration subcutaneous injection missed dose injection site reaction

This is a generated summary. It shows the 5 most-liked posts from a topic of 29, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.

two_year_lineTL3Regular27 Jun 2025#4

maintenance_mode, post #2: A genuinely late dose: the labelling generally says that if the next dose is more than a couple of days away, take it as soon as you notice. If the next dose is close, skip it and resume the schedule. The reasoning follows from the long half-life; you are perturbing a slowly moving average. Go to post

A site rotation scheme that actually works: abdomen, outer thigh, back of arm, outer hip. Rotate through them in order, move a minimum 2 cm between consecutive sites, note the site with each dose. If a local reaction appears you have the history. If you rotate properly you will not get lipohypertrophy from overuse of one area.

24 likes in reply to #2 13mo

bias_varianceTL4Biostatistician23 Jul 2025#8

post #7 answers the question as asked. The question underneath it is different.

Air bubbles in a subcutaneous injection: the honest risk assessment is low. Tiny air bubbles in subcutaneous tissue do not behave like an air embolism in a blood vessel. A few air bubbles are not a reason to restart the entire injection.

32 likes 12mo

integrator_draftTL3Regular20 Aug 2025#13

two_year_line, post #4: A site rotation scheme that actually works: abdomen, outer thigh, back of arm, outer hip. Rotate through them in order, move a minimum 2 cm between consecutive sites, note the site with each dose. If a local reaction appears you have the history. If you rotate properly you will not get lipohypertrophy from overuse of one area. Go to post

Drawing up with one needle and injecting with another: a reasonable practice if you have extra needles. Fresh needle for injection reduces tissue drag and can decrease discomfort. Not necessary, but not harmful either.

18 likes in reply to #4 11mo

bench_notesTL4 Moderator9 Oct 2025 · edited#23

s.kuusela, post #5: Angle of injection: 90 degrees into pinched tissue ensures subcutaneous placement. It is not always necessary and shallower angles can work, but 90 degrees into a small pinch is the safest technique to learn first. Go to post

27 likes in reply to #5 10mo

r.danquahTL2 Moderator27 Oct 2025#27

On post #23 — agreed on the reasoning, with one qualification.

Angle of injection: 90 degrees into pinched tissue ensures subcutaneous placement. It is not always necessary and shallower angles can work, but 90 degrees into a small pinch is the safest technique to learn first.

20 likes in reply to #4 9mo

Read the full topic (29 posts)

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