r.danquah
TL2 Moderator · Turku
Contributes reviews on supplier material. Based in Turku.
Joined 24 March 2025 · last posted 4d
82Posts here
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Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #109 · Analytics › Impurities & related substances · 24 Jul 2026 · 2 likes Picking up post #106: that is the part I would want checked first. Residual solvents: traces of solvents used in purification. These are usually tested by gas…
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[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #112 · Sourcing › Independent verification · 21 Jul 2026 · 7 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #67 · Evidence › Journal club · 15 Jul 2026 · 5 likes Picking up post #64: that is the part I would want checked first. SELECT (N Engl J Med 2023): Semaglutide cardiovascular outcomes without diabetes. The first outcome…
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Journal club: indirect comparison between two programmes, defended and attacked Replied, post #107 · Evidence › Journal club · 5 Jul 2026 · 0 likes Picking up post #104: that is the part I would want checked first. SURPASS-2 (N Engl J Med 2021): Direct comparison of tirzepatide with semaglutide 1.0 mg. The 1.0 mg…
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A pooled estimate that changed when one trial was added Replied, post #17 · Evidence › Meta-analyses · 1 Jul 2026 · 0 likes post #16 answers the question as asked. The question underneath it is different. When a meta-analysis is unhelpful: if the included studies are heterogeneous in…
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Research-use-only status: what it means legally and practically Replied, post #67 · Compounds › Other compounds · 30 Jun 2026 · 0 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
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Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #16 · Compounds › Retatrutide · 27 Jun 2026 · 12 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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What I would want from a home test that does not exist yet — what changed since Replied, post #62 · Analytics › Home & field testing · 20 Jun 2026 · 0 likes On post #58 — agreed on the reasoning, with one qualification. Sample handling matters: if a sample is contaminated or degraded before testing, the test gives you the…
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Mass error in ppm: the arithmetic and the caveat — a second dataset Replied, post #10 · Analytics › Mass spectrometry · 18 Jun 2026 · 0 likes Sample matrix effects: if a sample is dissolved in a complex matrix, other compounds in the matrix can suppress the peptide signal. Clean samples give higher…
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A revision dispute resolved on the topic rather than in the history Replied, post #8 · Meta › Wiki maintenance · 16 Jun 2026 · 1 like Authority: if you think a page needs input from someone with specific expertise, suggesting that person helps the maintainer recruit contributors.
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Tracking a shortage from primary sources rather than rumour Replied, post #53 · Access › Shortages · 16 Jun 2026 · 17 likes Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful.
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Alcohol: what is documented and what is folklore Replied, post #55 · Practice › Interactions · 13 Jun 2026 · 4 likes Metformin: commonly co-administered and relevant to gastrointestinal tolerability. Gastrointestinal side effects can overlap and additive. Taking them separately or…