Topic summary

Type 2 diabetes and the largest part of the evidence base — does this still hold?

Clinical › Comorbidities type 2 diabetes chronic kidney disease PCOS blood pressure MASH / hepatic steatosis Solved

This is a generated summary. It shows the 5 most-liked posts from a topic of 23, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.

v.bhattacharyaTL2 Moderator4 Apr 2026#3

e.almeida, post #1: Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Asking about a population rather than about a person. The published trials in this class mostly enrolled a fairly specific group, and the questions here frequently… Go to post

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

26 likes in reply to #1 4mo

f.fonsecaTL2 Moderator Solution8 May 2026#8

PCOS and metabolic overlap: polycystic ovary syndrome has metabolic overlap with obesity and insulin resistance. Data on compounds in this class in PCOS specifically is thin; most discussion is by mechanism.

8 likes 3mo

excursion_checkTL3Regular12 Jun 2026#14

Type 2 diabetes: the population with the largest evidence base for these compounds. The SURPASS and SUSTAIN programmes established glycaemic benefit. The renal and cardiovascular benefit evidence is separate from the glycaemic benefit evidence.

31 likes 2mo

PSkarbekTL3Regular2 Jul 2026#18

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

23 likes 26d

i.amankwahTL2 Moderator7 Jul 2026 · edited#19

post #18 answers the question as asked. The question underneath it is different.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

32 likes 21d

Read the full topic (23 posts)

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