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Evidence · Preprints · continued

When a preprint is the best available evidence and we say so posts 121–150

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

CG
c.grimaldiTL2 Moderator31 Aug 2025#121

I read post #119 twice before replying, because I had assumed the opposite.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

13 likes 11mo
CC
c.cardosoTL2 Moderator31 Aug 2025 · edited#122
a.frisk, post #51: Coming back to post #49, because the follow-up matters more than the original answer. How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint. Go to post

This follows post #119 rather than contradicting it.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

4 likes in reply to #51 11mo
ML
m.lehtinenTL2 Moderator31 Aug 2025#123

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

0 likes 11mo
NN
n.nybergTL2 Moderator1 Sep 2025#124

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

27 likes 11mo
CL
c.lundgrenTL2 Moderator1 Sep 2025#125

Coming back to post #123, because the follow-up matters more than the original answer.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

8 likes 11mo
HE
h.eriksenTL2 Moderator1 Sep 2025#126
d.bakker, post #39: Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished. Go to post

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

2 likes in reply to #39 11mo
ZL
z.laurentTL2 Moderator1 Sep 2025#127

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

0 likes 11mo
DY
d.yilmazTL2 Moderator2 Sep 2025#128

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

20 likes 11mo
AW
a.westergaardTL3Regular2 Sep 2025#129

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

26 likes 11mo
CF
c.falkTL2 Moderator2 Sep 2025#130

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

12 likes 11mo
BT
b.teixeiraTL2 Moderator2 Sep 2025#131

post #130 answers the question as asked. The question underneath it is different.

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

21 likes 11mo
D
DOdendaalTL3Regular3 Sep 2025#132

On post #128 — agreed on the reasoning, with one qualification.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

0 likes 11mo
NZ
n.zielinskiTL2 Moderator3 Sep 2025 · edited#133
integrator_trace, post #111: This follows post #108 rather than contradicting it. For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use. Go to post

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

2 likes in reply to #111 11mo
M
MJayawardenaTL3Regular3 Sep 2025#134

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

9 likes 11mo
ER
e.roosTL2 Moderator3 Sep 2025#135

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

28 likes 11mo
SG
s.grahameTL2Member3 Sep 2025#136

Worth separating two things that post #132 runs together.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

0 likes 11mo
RI
r.ilungaTL2 Moderator4 Sep 2025#137
d.yilmaz, post #128: Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised. Go to post

This follows post #134 rather than contradicting it.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

5 likes in reply to #128 11mo
ED
e.dalgleishTL3Regular4 Sep 2025#138

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

14 likes 11mo
PD
p.dialloTL2 Moderator4 Sep 2025#139

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

9 likes 11mo
B
BirkelandTL3Regular4 Sep 2025#140

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

21 likes 11mo
RL
r.lundgrenTL2 Moderator5 Sep 2025#141

On post #137 — agreed on the reasoning, with one qualification.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

30 likes 11mo
QZ
q.zhao_qaTL3Quality assurance5 Sep 2025#142

post #141 answers the question as asked. The question underneath it is different.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

15 likes 11mo
ZC
z.cardosoTL25 Sep 2025#143
DM
d.moreauTL2Regular5 Sep 2025#144
e.kimani, post #106: What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

1 like in reply to #106 11mo
BD
b.dumitruTL2 Moderator6 Sep 2025#145

Worth separating two things that post #141 runs together.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

22 likes 11mo
EN
electrolyte_notesTL2Regular6 Sep 2025#146

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

10 likes 11mo
VB
v.bruunTL2 Moderator6 Sep 2025 · edited#147

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

3 likes 11mo
NT
nl_translatorTL2Translator · NL6 Sep 2025#148
r.erdogan, post #94: Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions. Go to post

This follows post #145 rather than contradicting it.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

0 likes in reply to #94 11mo
CO
c.ostergaardTL2 Moderator6 Sep 2025#149
t.duarte, post #92: This follows post #89 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up. Go to post

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

16 likes in reply to #92 11mo
HS
hana.satoTL4 Moderator7 Sep 2025#150

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

6 likes 11mo