e.kimani
TL2 Moderator · Funchal
Contributes reviews on supplier material. Based in Funchal.
Joined 27 January 2025 · last posted 2d
91Posts here
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[2026 update] A report I filed that turned out to be wrong, and the correction Replied, post #20 · Sourcing › Vendor reports · 26 Jul 2026 · 8 likes Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion, and excipient. Purity and content are…
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Coming back to: Telehealth prescribing models in the US Replied, post #28 · Regional › North America · 25 Jul 2026 · 22 likes Private insurance gaps: some people have private insurance but medication is not covered. Manufacturer assistance programmes are the main resource for cost reduction.
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Journal club: what we got wrong in an earlier session Replied, post #111 · Evidence › Journal club · 23 Jul 2026 · 0 likes SURMOUNT-OSA (N Engl J Med 2024): Tirzepatide in obstructive sleep apnoea, using an objective physiological endpoint. Notable because soft endpoints are avoided. Two…
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Coming back to: Where the four-week escalation interval comes from, and what it is not Replied, post #39 · Practice › Dosing & titration · 21 Jul 2026 · 0 likes Worth separating two things that post #35 runs together. When a dose reduction is the correct response to a side effect: if a side effect is dose-dependent (nausea,…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #89 · Evidence › Journal club · 20 Jul 2026 · 28 likes FLOW (N Engl J Med 2024): Semaglutide renal outcomes in type 2 diabetes and chronic kidney disease. Stopped early for efficacy. Component-by-component analysis is…
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NHS criteria and how they are applied in practice Replied, post #34 · Regional › UK & Ireland · 18 Jul 2026 · 0 likes Cross-border arrangements: some people source from other EU countries. Rules on import for personal use are changing post-Brexit. Current status requires checking with…
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[2026 update] Regional warehouse stock versus direct despatch Replied, post #137 · Sourcing › Logistics · 17 Jul 2026 · 17 likes Insurance and carrier liability: most parcel carriers limit liability. Understanding the limits before choosing a carrier matters if you are shipping expensive material.
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Micro-titration: a disputed topic, argued properly — one year on Replied, post #63 · Practice › Dosing & titration · 14 Jul 2026 · 23 likes Dose equivalence between different incretin analogues is a weak concept. The molecules differ in structure, half-life, receptor selectivity, and in what has been…
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Here for the analytics and not much else Replied, post #27 · Lounge › Introductions · 13 Jul 2026 · 16 likes No spam: introductions are not a place to advertise commercial products or services. That is a rules violation.
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Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #22 · Evidence › Meta-analyses · 3 Jul 2026 · 2 likes Funnel plots: a plot of study effect size versus sample size that helps detect publication bias. If small studies are missing on the negative side, the funnel is…
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Historical amylin analogues and what happened to them Replied, post #26 · Compounds › Cagrilintide & amylin analogues · 1 Jul 2026 · 0 likes What is genuinely unknown about long-term amylin agonism: real-world response rates, whether effect is durable with continued use, whether satiety adaptation occurs…
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I have no scientific background — can I still follow the analytics categories? Replied, post #29 · Start Here › Welcome · 29 Jun 2026 · 0 likes I read post #27 twice before replying, because I had assumed the opposite. Off-topic posts that do not belong here belong in the Lounge instead. You are not in trouble…