e.pires

TL2 Moderator · Uppsala

Contributes reviews on supplier material. Based in Uppsala.

Joined 21 August 2025 · last posted 23h

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What a reversed-phase purity number actually is Replied, post #99 · Analytics › HPLC & UHPLC · 27 Jul 2026 · 1 like Gradient slope is the single biggest driver of apparent purity differences. A shallower gradient over a longer run resolves more impurities and gives a higher purity…
What to bring: records that a clinician can actually use Replied, post #19 · Clinical › Prescriber conversations · 26 Jul 2026 · 18 likes Preparing for an appointment: bring recent bloodwork, a list of current medications with doses and timing, and any questions written out. Written questions get better…
Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #115 · Analytics › Impurities & related substances · 26 Jul 2026 · 18 likes Disulfide formation: if a peptide contains cysteine, it can form disulfide bonds with itself or with other molecules. Under oxidising conditions multiple species…
Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #75 · Practice › Side effects · 25 Jul 2026 · 1 like On post #71 — agreed on the reasoning, with one qualification. Constipation: common, manageable, and frequently under-reported because it is not dramatic. Increasing…
Reading U-100 graduations, with a conversion table Replied, post #41 · Devices › Syringes & needles · 22 Jul 2026 · 21 likes Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take…
Asking a follow-up: new topic or new reply? Replied, post #62 · Start Here › How to Ask · 20 Jul 2026 · 14 likes Disagreement-style questions: "I read this and it contradicts what I heard here, which is right?" is answerable. "Is this a bad idea?" without giving the context is not.
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #103 · Sourcing › Vendor reports · 17 Jul 2026 · 32 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Review: a draft on reconstitution arithmetic, with objections — one year on Replied, post #44 · Documentation › Doc review · 14 Jul 2026 · 9 likes Review date disputes: if a maintained page's review date is approaching and it has not been updated, post a note so the maintainers notice.
Request: a per-category review queue Replied, post #85 · Meta › Feature requests · 7 Jul 2026 · 0 likes Community support: if other people support your request, they can reply with "+1" or "I would use that too". Widely-requested features are prioritised.
How much context is too much context in a first post? Replied, post #22 · Start Here › How to Ask · 6 Jul 2026 · 19 likes post #21 answers the question as asked. The question underneath it is different. Asking a follow-up: new topic or reply in the old one? If the answer depends on the…
A single out-of-range value on an otherwise normal panel Replied, post #67 · Clinical › Bloodwork · 2 Jul 2026 · 9 likes Reference intervals: constructed to contain the central 95% of a reference population, which means one in twenty healthy people falls outside one by definition. Add…
Pages past their review date, listed — does this still hold? Replied, post #19 · Meta › Wiki maintenance · 20 Jun 2026 · 0 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…