glossary_line
TL1 Member · Bordeaux, FR
Joined after a search result brought me to one of the reconstitution pages. Stayed for the tone.
Joined 2 March 2025 · last posted 1mo
24Posts here
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Run-in periods and the population they select Replied, post #74 · Evidence › Trials · 1 Mar 2026 · 31 likes Dropout is information: high dropout rates can indicate tolerability problems or lower efficacy than the summary suggests. Where the analysis handled dropouts matters.…
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A field-by-field walk through a certificate of analysis Replied, post #25 · Analytics › COA interpretation · 14 Jul 2025 · 29 likes This follows post #22 rather than contradicting it. A certificate of analysis is a statement by its issuer that a defined test was performed on a defined lot and…
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Follow-up: Individual participant data versus aggregate data Replied, post #9 · Evidence › Meta-analyses · 8 Jan 2025 · 27 likes Funnel plots: a plot of study effect size versus sample size that helps detect publication bias. If small studies are missing on the negative side, the funnel is…
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Column chemistry choices for a 40-residue peptide Replied, post #4 · Analytics › HPLC & UHPLC · 30 Jul 2025 · 24 likes the opening post is right about the mechanism and I think understates the practical bit. On integration: where the baseline is drawn matters more than most people…
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[2026 update] A rising related-substance total over six months: degradation or method… Replied, post #30 · Analytics › Impurities & related substances · 13 Feb 2026 · 12 likes Oxidation at methionine and tryptophan: adds 16 per oxygen. Usually elutes earlier. Oxidation is common in storage, especially if the solution is exposed to light or if…
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Progressive overload when the scale is falling Started this topic · Nutrition & Training › Resistance training · 2 Mar 2025 · 12 likes Posting this under the heading it deserves: Progressive overload when the scale is falling Everything below is what sits behind that. Longitudinal report with the…
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Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| Read the Guidelines | bronze | 3 Mar 2025 |
| First Reply | bronze | 5 Mar 2025 |
| Basic User | bronze | 6 Mar 2025 |
| Welcome | bronze | 7 Mar 2025 |
| Asked Well | bronze | 8 Mar 2025 |
| First Link | bronze | 19 Mar 2025 |
| First Topic | bronze | 27 Mar 2025 |
| First Quote | bronze | 8 Apr 2025 |
| Nice Post | bronze | 23 May 2025 |
| Nice Topic | bronze | 24 Jun 2025 |
| Good Post | silver | 5 Aug 2025 |
| Anniversary | silver | 2 Mar 2026 |