h.castellanos
TL2 Moderator · Antalya
Contributes reviews on supplier material. Based in Antalya.
Joined 20 September 2024 · last posted 3d
86Posts here
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Follow-up: Subcutaneous absorption kinetics and site differences Started this topic · Pharmacology › Pharmacokinetics · 7 Oct 2025 · 39 likes Subcutaneous absorption kinetics and site differences — setting out what I have, and where I think it stops being reliable. I would like to understand what this number…
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Tirzepatide in type 2 diabetes: the SURPASS programme, summarised honestly Replied, post #52 · Compounds › Tirzepatide · 2 Apr 2025 · 31 likes Half-life difference: tirzepatide is about 5 days versus semaglutide's week-long. Practically, that means steady state is reached slightly faster and the post-dose…
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Journal club: SURMOUNT-4 and continuation versus withdrawal Replied, post #16 · Evidence › Journal club · 27 Mar 2026 · 29 likes SURPASS-2 (N Engl J Med 2021): Direct comparison of tirzepatide with semaglutide 1.0 mg. The 1.0 mg dose is not the highest available, which is the central and…
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Reconstituting a multi-strength kit without mixing yourself up — what changed since Replied, post #28 · Practice › Reconstitution · 16 Jun 2026 · 28 likes A 10 mg vial reconstituted three different ways: 1 mL diluent gives 10 mg/mL, 2 mL gives 5 mg/mL, 4 mL gives roughly 2.5 mg/mL. The arithmetic is the same; the…
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A 40-week log with the measurement method stated Replied, post #85 · Outcomes › Progress reports · 28 Oct 2025 · 26 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
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The mass-error checker and its intended scope Replied, post #34 · Data & Tools › Calculators · 7 Jun 2024 · 24 likes Why calculators are not medical advice: they do arithmetic. Medical decisions are not arithmetic. A calculator that says a certain dose is "compatible with" a certain…
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