n.cardoso

TL2 Moderator · Ghent

Contributes reviews on supplier material. Based in Ghent.

Joined 13 April 2025 · last posted 5d

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Aggregate verification data across the directory, with caveats Replied, post #65 · Sourcing › Independent verification · 23 Jul 2026 · 0 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
Batch numbers that do not match the vial label Replied, post #47 · Sourcing › Red flags · 22 Jul 2026 · 2 likes I read post #45 twice before replying, because I had assumed the opposite. Unresponsiveness: a supplier that does not reply to reasonable requests for documentation or…
Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #99 · Analytics › Impurities & related substances · 21 Jul 2026 · 26 likes Deamidation at asparagine and glutamine: adds 1 approximately. Frequently appears as a close-eluting pair. It is a chemical modification that occurs during storage.
[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #108 · Sourcing › Independent verification · 20 Jul 2026 · 1 like post #107 is right about the mechanism and I think understates the practical bit. How to submit a sample: contact the service directly. They will provide instructions…
Substitution between formats during a shortage — what changed since Replied, post #19 · Access › Shortages · 18 Jul 2026 · 16 likes This follows post #16 rather than contradicting it. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and…
Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #76 · Evidence › Journal club · 17 Jul 2026 · 1 like This follows post #73 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
Request: a per-category review queue Replied, post #109 · Meta › Feature requests · 17 Jul 2026 · 15 likes post #108 answers the question as asked. The question underneath it is different. For anyone arriving from a search: the marked solution above is the direct answer, and…
Journal club: indirect comparison between two programmes, defended and attacked Replied, post #116 · Evidence › Journal club · 13 Jul 2026 · 0 likes This follows post #113 rather than contradicting it. SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the cardiovascular evidence to the oral…
Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #81 · Analytics › Method validation · 7 Jul 2026 · 0 likes Picking up post #78: that is the part I would want checked first. Limits of detection and quantitation: LOD is the lowest concentration that produces a signal above…
Aggregate verification data across the directory, with caveats Replied, post #25 · Sourcing › Independent verification · 3 Jul 2026 · 0 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
What I would want from a home test that does not exist yet — what changed since Replied, post #73 · Analytics › Home & field testing · 29 Jun 2026 · 0 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
About the HPLC & UHPLC category Replied, post #4 · Analytics › HPLC & UHPLC · 23 Jun 2026 · 25 likes Suggestion for the wiki post above: it would be worth linking the two or three most-referenced topics in this category directly, since new members reliably ask for…