n.osei

TL2 Moderator · Uppsala

Contributes reviews on supplier material. Based in Uppsala.

Joined 10 June 2025 · last posted 5d

86Posts here

1Topics

1Solutions

1.1kLikes received

1.3kLikes given

23Badges

206Days visited

4.3kPosts read

Recent activity

Full stream

Immortal time bias in a claims-database study — one year on Replied, post #39 · Evidence › Study critique · 23 Jul 2026 · 9 likes Worth separating two things that post #35 runs together. Multiple comparisons: if a paper reports many outcomes, the chance of a spurious association by random chance…
What to bring: records that a clinician can actually use Replied, post #8 · Clinical › Prescriber conversations · 19 Jul 2026 · 18 likes Clarifying indication: if a compound is approved for diabetes but you have obesity without diabetes, clarify whether your clinician considers this off-label use and…
[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #36 · Analytics › HPLC & UHPLC · 14 Jul 2026 · 10 likes On post #32 — agreed on the reasoning, with one qualification. System suitability testing: injections run before and during the sample run to establish whether the…
Here for the analytics and not much else Replied, post #30 · Lounge › Introductions · 13 Jul 2026 · 31 likes What to include: your name or handle, how you found the community, what brings you here, maybe something about yourself that seems relevant (clinician, researcher,…
Pages past their review date, listed — does this still hold? Replied, post #42 · Meta › Wiki maintenance · 7 Jul 2026 · 26 likes Scope creep: if a page is attempting too much, suggesting it split into multiple pages can improve clarity.
How much context is too much context in a first post? Replied, post #4 · Start Here › How to Ask · 4 Jul 2026 · 1 like Five questions in one post gets you one answer: the easiest one, usually not the one you needed most. Post them separately or pick the one that depends on the others…
Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #33 · Compounds › Retatrutide · 3 Jul 2026 · 0 likes How to read phase 2 without treating it as phase 3: phase 2 establishes that a dose range produces an effect and is tolerable enough to justify large trials. It does…
What consumer-accessible tests can and cannot determine — a second dataset Replied, post #46 · Analytics › Home & field testing · 2 Jul 2026 · 27 likes Lateral-flow devices: like a rapid COVID test. They have a reagent strip and produce a colour result. They are quick but not precise and not intended for quantitative…
Carryover and the ghost peak from last week's standard — what changed since Replied, post #91 · Analytics › HPLC & UHPLC · 30 Jun 2026 · 0 likes Peak purity: a diode-array detector records a spectrum at every time point. If a peak contains two co-eluting species with different spectra, the spectrum changes…
Does dual agonism explain the effect size, or is it dose? Replied, post #65 · Compounds › Tirzepatide · 27 Jun 2026 · 9 likes On post #61 — agreed on the reasoning, with one qualification. Mass and charge states: tirzepatide is about 4813.5 Da and on an electrospray instrument you would expect…
Carryover and the ghost peak from last week's standard — what changed since Replied, post #72 · Analytics › HPLC & UHPLC · 25 Jun 2026 · 0 likes Coming back to post #70, because the follow-up matters more than the original answer. Column chemistry and particle size: smaller particles (1.7 μm) give better…
Submitting a sample: the process end to end Replied, post #34 · Sourcing › Independent verification · 23 Jun 2026 · 32 likes Interpreting a result: a purity figure is one measurement on one vial on one day. Agreement across two services is much stronger. A single high number does not…