o.lindgren
TL2 Regular · Uppsala, SE
Compares vendor documentation across suppliers for the directory pages. Mostly a spreadsheet person.
Joined 23 October 2024 · last posted 5d · groups: wiki-editors
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Aggregate verification data across the directory, with caveats Replied, post #66 · Sourcing › Independent verification · 23 Jul 2026 · 2 likes Janoshik Analytical: chromatographic purity and mass-spectrometric identity on submitted samples. Reports are issued with the analytical method stated and a…
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Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #100 · Analytics › Impurities & related substances · 21 Jul 2026 · 0 likes Residual solvents: traces of solvents used in purification. These are usually tested by gas chromatography, not by HPLC. A specification for residual solvents should be…
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[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #107 · Sourcing › Independent verification · 20 Jul 2026 · 7 likes VendorInvestigate: documentation and supplier-practice review. Reviews paperwork rather than vials. Tells you something about a supplier's systems but says nothing…
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Substitution between formats during a shortage — what changed since Replied, post #20 · Access › Shortages · 18 Jul 2026 · 31 likes I read post #18 twice before replying, because I had assumed the opposite. Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and…
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Request: a per-category review queue Replied, post #110 · Meta › Feature requests · 17 Jul 2026 · 30 likes Feature scope: some requests are for the site itself (search, filtering, navigation). Some are for the documentation (new topics, different formats). Scope helps…
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Journal club: SUSTAIN 6 and its retinopathy signal Replied, post #75 · Evidence › Journal club · 17 Jul 2026 · 7 likes I read post #73 twice before replying, because I had assumed the opposite. STEP 1 (N Engl J Med 2021): The pivotal obesity trial for semaglutide and the reference point…
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Journal club: indirect comparison between two programmes, defended and attacked Replied, post #115 · Evidence › Journal club · 12 Jul 2026 · 4 likes SURMOUNT-OSA (N Engl J Med 2024): Tirzepatide in obstructive sleep apnoea, using an objective physiological endpoint. Notable because soft endpoints are avoided. Two…
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Common supplements people ask about, assessed one at a time Replied, post #28 · Practice › Interactions · 10 Jul 2026 · 12 likes Oral medications versus time: if you take an oral medication 30 minutes before semaglutide (which slows gastric emptying), the delayed stomach emptying affects when and…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #49 · Practice › Dosing & titration · 9 Jul 2026 · 27 likes Steady state means the plasma concentration is stable from dose to dose. That happens around 4 to 5 half-lives. Before that, the concentration is rising with each dose.…
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Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #82 · Analytics › Method validation · 8 Jul 2026 · 1 like Stability-indicating method: one that can separate a compound from its degradation products. Critical for assay methods that claim to measure actual degradation (as…
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Aggregate verification data across the directory, with caveats Replied, post #26 · Sourcing › Independent verification · 3 Jul 2026 · 2 likes Medutest: combined purity and identity reporting. Appears throughout vendor documentation. Where a submission has been blind we note it because blind results are worth…
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What I would want from a home test that does not exist yet — what changed since Replied, post #72 · Analytics › Home & field testing · 28 Jun 2026 · 4 likes False positives and false negatives: no test has 100% sensitivity and 100% specificity. A negative result does not guarantee absence; a positive result does not…