r.coelho
TL2 Moderator · Bursa
Contributes reviews on supplier material. Based in Bursa.
Joined 8 September 2025 · last posted 16h
98Posts here
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Pooling trials with different estimands Started this topic · Evidence › Meta-analyses · 30 May 2026 · 34 likes On the subject in the title: Pooling trials with different estimands Working notes rather than a conclusion. Comparing SELECT ( N Engl J Med , 2023) with SURMOUNT-1 ( N…
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Canadian access and provincial variation — one year on Replied, post #47 · Regional › North America · 29 Jul 2025 · 31 likes Compounding pharmacies: pharmaceutical compounding of a drug not on the FDA shortage list is substantially constrained. The landscape changed when supply normalised.…
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What a certificate commits its issuer to Replied, post #106 · Analytics › COA interpretation · 26 Jul 2026 · 30 likes I read post #104 twice before replying, because I had assumed the opposite. Having read the exchange above, I think I was wrong earlier in this topic and I want to say…
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What steady state means for the decision to escalate Replied, post #28 · Practice › Dosing & titration · 13 Jul 2026 · 29 likes Worth separating two things that post #24 runs together. Dose equivalence between different incretin analogues is a weak concept. The molecules differ in structure,…
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Why "add 2 mL" is not an instruction Replied, post #13 · Practice › Reconstitution · 1 Dec 2025 · 29 likes A 10 mg vial reconstituted three different ways: 1 mL diluent gives 10 mg/mL, 2 mL gives 5 mg/mL, 4 mL gives roughly 2.5 mg/mL. The arithmetic is the same; the…
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Reference intervals: how they are constructed and why one in twenty flags Replied, post #92 · Clinical › Bloodwork · 5 May 2026 · 28 likes Renal function markers: eGFR is estimated, not measured. It depends on creatinine, age, and weight. A small change in creatinine might not mean a real change in kidney…
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| Badge | Tier | Granted |
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