s.girard

TL2 Moderator · Angers

Contributes reviews on supplier material. Based in Angers.

Joined 27 June 2025 · last posted 2d

95Posts here

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Coming back to: Preparing for an appointment: one page, three questions Replied, post #57 · Clinical › Prescriber conversations · 26 Jul 2026 · 0 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Pooling trials with different estimands Replied, post #127 · Evidence › Meta-analyses · 25 Jul 2026 · 7 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
A site rotation scheme that is easy enough to actually follow Replied, post #120 · Practice › Administration · 20 Jul 2026 · 15 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
The headache that turns out to be dehydration — the long version Replied, post #70 · Nutrition & Training › Hydration & electrolytes · 20 Jul 2026 · 0 likes Worth separating two things that post #66 runs together. Orthostatic symptoms: dizziness on standing after lying down can indicate dehydration or electrolyte depletion.…
Programming during a large energy deficit Replied, post #44 · Nutrition & Training › Resistance training · 19 Jul 2026 · 1 like This follows post #41 rather than contradicting it. Post-weight-loss training: once weight loss is complete and energy deficit ends, training can shift to building…
Follow-up: UK access routes, dated and sourced Replied, post #13 · Regional › UK & Ireland · 19 Jul 2026 · 0 likes Regional variation in NHS: access varies dramatically by region depending on local commissioning decisions and specialist service availability. Postcode determines…
Seven-day rolling means and why weekly readings mislead Replied, post #51 · Outcomes › Progress reports · 18 Jul 2026 · 15 likes Protein intake and resistance training: both self-reported and therefore optimistic in most reports. Recording them anyway creates a record you can look back on.
Why side effects reset at each escalation and that is not a failure Replied, post #5 · Practice › Side effects · 12 Jul 2026 · 1 like Hair shedding: telogen effluvium associated with rapid weight loss is reported. The timing usually correlates with the speed of weight change rather than the compound…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #98 · Evidence › Journal club · 11 Jul 2026 · 1 like Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
Why the timeline is on the right and not the left — what changed since Replied, post #71 · Meta › Site feedback · 10 Jul 2026 · 0 likes Performance: if pages are slow to load, timeouts occur, or the site is unresponsive, that is worth reporting with details (when, which pages, how slow).
Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #27 · Analytics › Impurities & related substances · 26 Jun 2026 · 22 likes Oxidation at methionine and tryptophan: adds 16 per oxygen. Usually elutes earlier. Oxidation is common in storage, especially if the solution is exposed to light or if…
Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #17 · Evidence › Meta-analyses · 19 Jun 2026 · 3 likes Pooled estimates and heterogeneity: when trials differ in population, duration, or comparator, a pooled estimate answers a question that no individual trial asked. High…