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Access · Shortages · continued

Substitution between formats during a shortage posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

DY
d.yilmazTL2 Moderator31 Jul 2025#31
d.nilsen, post #27: This follows post #24 rather than contradicting it. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer. Go to post

Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information.

32 likes in reply to #27 12mo
AW
a.westergaardTL3Regular2 Aug 2025#32

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

17 likes 12mo
CF
c.falkTL2 Moderator4 Aug 2025#33

Worth separating two things that post #29 runs together.

Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful.

6 likes 12mo
SE
septum_entryTL2Member6 Aug 2025#34

Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.

1 like 12mo
NN
n.nybergTL2 Moderator7 Aug 2025#35
d.nilsen, post #27: This follows post #24 rather than contradicting it. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer. Go to post

Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for planning.

0 likes in reply to #27 12mo
CL
c.lundgrenTL2 Moderator9 Aug 2025#36
f.danquah, post #20: post #19 is right about the mechanism and I think understates the practical bit. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer. Go to post

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

23 likes in reply to #20 12mo
HE
h.eriksenTL2 Moderator11 Aug 2025#37

On post #33 — agreed on the reasoning, with one qualification.

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

11 likes 12mo
ZL
z.laurentTL213 Aug 2025#38
DO
dr_okonkwoTL4 Moderator15 Aug 2025#39
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

I read post #37 twice before replying, because I had assumed the opposite.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

17 likes 11mo
CG
c.grimaldiTL2 Moderator17 Aug 2025#40

Resuming after a gap: after a gap of days or a few weeks, most people resume at the dose they were on when they stopped. Gaps of months might require retitration discussion with a clinician.

7 likes 11mo
DB
d.barrosTL2 Moderator18 Aug 2025#41
a.molnar, post #4: Worth separating two things that post #2 runs together. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had been repeating something I had not checked carefully enough. Go to post

Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.

0 likes in reply to #4 11mo
NP
n.petrovTL2 Moderator20 Aug 2025#42

Coming back to post #40, because the follow-up matters more than the original answer.

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

1 like 11mo
AS
a.silvaTL2 Moderator22 Aug 2025#43

post #42 answers the question as asked. The question underneath it is different.

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

10 likes 11mo
MI
m.ivaturiTL2 Moderator24 Aug 2025#44

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

22 likes 11mo
SC
so.cardosoTL2 Moderator26 Aug 2025#45
a.westergaard, post #9: Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice. Go to post

This follows post #42 rather than contradicting it.

Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.

31 likes in reply to #9 11mo
VB
va.baptistaTL2 Moderator27 Aug 2025#46
r.venkatesan, post #19: Worth separating two things that post #15 runs together. Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for planning. Go to post

I read post #44 twice before replying, because I had assumed the opposite.

Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information.

0 likes in reply to #19 11mo
BN
b.nilsenTL2 Moderator29 Aug 2025#47

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

6 likes 11mo
SD
s.dziedzicTL2 Moderator31 Aug 2025#48

Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions.

16 likes 11mo
CR
compounding_ruthTL4Pharmacist2 Sep 2025#49
n.petrov, post #42: Coming back to post #40, because the follow-up matters more than the original answer. Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage). Go to post

Picking up post #46: that is the part I would want checked first.

Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for planning.

23 likes in reply to #42 11mo
HD
h.delgadoTL2 Moderator3 Sep 2025#50
cohort_watch, post #5: Picking up post #2: that is the part I would want checked first. International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

0 likes in reply to #5 11mo
FK
f.kimaniTL2 Moderator5 Sep 2025#51

On post #47 — agreed on the reasoning, with one qualification.

Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.

29 likes 11mo
ZO
z.onwukaTL2 Moderator7 Sep 2025#52

Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful.

15 likes 11mo
JP
j.petrovTL2 Moderator8 Sep 2025#53
r.ilunga, post #21: Patient advocacy during shortages: some advocacy groups advocate for patients during shortages. Knowing who they are and following their communication is useful. Go to post

Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for planning.

3 likes in reply to #21 11mo
TV
t.vasquezTL4 Moderator10 Sep 2025#54
d.yilmaz, post #10: Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive. Go to post
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

0 likes in reply to #10 11mo
CD
c.dahlbergTL2 Moderator12 Sep 2025 · edited#55

Worth separating two things that post #51 runs together.

Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions.

0 likes 10mo
IC
i.coelhoTL2 Moderator13 Sep 2025#56

post #55 is right about the mechanism and I think understates the practical bit.

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

21 likes 10mo
MR
m.rasmussenTL2 Moderator15 Sep 2025#57
integrator_trace, post #17: Coming back to post #15, because the follow-up matters more than the original answer. Communication from suppliers: a supplier having supply problems usually communicates them. If a supplier goes silent, that is itself information. Go to post

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

5 likes in reply to #17 10mo
JB
j.baptistaTL2 Moderator17 Sep 2025#58

Resuming after a gap: after a gap of days or a few weeks, most people resume at the dose they were on when they stopped. Gaps of months might require retitration discussion with a clinician.

0 likes 10mo
DF
d.ferreiraTL2 Moderator18 Sep 2025#59

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

15 likes 10mo
BV
bias_varianceTL4Biostatistician20 Sep 2025#60
i.coelho, post #56: post #55 is right about the mechanism and I think understates the practical bit. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer. Go to post

post #59 answers the question as asked. The question underneath it is different.

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

6 likes in reply to #56 10mo