b.nilsen
TL2 Moderator · Kristiansand
Contributes reviews on supplier material. Based in Kristiansand.
Joined 19 March 2025 · last posted 2d
66Posts here
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Journal club: what we got wrong in an earlier session Replied, post #121 · Evidence › Journal club · 25 Jul 2026 · 13 likes FLOW (N Engl J Med 2024): Semaglutide renal outcomes in type 2 diabetes and chronic kidney disease. Stopped early for efficacy. Component-by-component analysis is…
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Reading a home test result without over-claiming Replied, post #124 · Analytics › Home & field testing · 18 Jul 2026 · 19 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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Revisiting: The best-written scientific paper you have read Replied, post #97 · Lounge › Off topic · 17 Jul 2026 · 0 likes Worth separating two things that post #93 runs together. Not a rules-free zone: the guidelines still apply. No phones, no Telegram, no endorsements of other…
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #54 · Practice › Side effects · 16 Jul 2026 · 0 likes Gallbladder complications: rapid weight loss increases the risk of gallstone formation. The mechanism is not specific to this drug class. The risk is greatest in the…
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What is genuinely unknown about long-term amylin agonism Replied, post #36 · Compounds › Cagrilintide & amylin analogues · 14 Jul 2026 · 0 likes Historical amylin analogues: pramlintide was the only long-acting amylin analogue licensed for some time and its poor adherence was a known limitation. A weekly…
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Pooling trials with different estimands Replied, post #83 · Evidence › Meta-analyses · 9 Jul 2026 · 31 likes Why forest plots are more informative than pooled numbers: they show the variation across studies, which tells you whether the effect is consistent or heterogeneous. A…
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Coming back to: Time to steady state after a dose increase Replied, post #77 · Pharmacology › Pharmacokinetics · 15 Jun 2026 · 1 like Hepatic metabolism: the degree to which each compound is hepatically metabolised versus renally cleared is known but varies. Severe liver disease changes clearance.
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #16 · Access › Insurance & coverage · 11 Jun 2026 · 0 likes Appeals process: unemotional prose, the criterion quoted verbatim, evidence mapped to it point by point, dates, and nothing else. Describing how the decision affected…
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[2026 update] Area percent versus weight percent: the confusion that causes most arguments Replied, post #51 · Analytics › HPLC & UHPLC · 31 May 2026 · 4 likes Method validation is the demonstration that a method can separate the compound from its degradation products and impurities reliably. A method that cannot resolve an…
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Second pass at: Metformin co-administration and additive GI effects Replied, post #88 · Practice › Interactions · 19 Apr 2026 · 8 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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[2026 update] 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #19 · Devices › Syringes & needles · 9 Apr 2026 · 1 like On post #15 — agreed on the reasoning, with one qualification. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly…
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Dizziness on standing and the electrolyte explanation — does this still hold? Replied, post #65 · Practice › Side effects · 6 Apr 2026 · 3 likes Coming back to post #63, because the follow-up matters more than the original answer. Nausea: the most common side effect and the most dose- and titration-dependent…