Why "add 2 mL" is not an instruction — a second dataset — that is the question, and I have not found it answered plainly anywhere I have looked.
Reporting something rather than asking about it, in case the pattern is useful to anyone else.
Over 11 weeks I logged this consistently: date, dose, time of day, and a simple severity score from 0 to 4 for each symptom. That is 88 data points, all self-reported, all unblinded, and collected by someone who knew what he expected to find. Treat it accordingly.
The reason I am posting is that my experience does not match the shape people usually describe here, and I would like to know whether that is unusual or whether the usual description is just the loudest version.