Bramley
TL2 Member · Trento, IT
Keeps a personal log and shares the numbers when they are relevant, with the measurement caveats attached.
Joined 12 May 2025 · last posted 10d
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What I would want from a home test that does not exist yet — what changed since Replied, post #99 · Analytics › Home & field testing · 18 Jul 2026 · 11 likes On post #95 — agreed on the reasoning, with one qualification. False positives and false negatives: no test has 100% sensitivity and 100% specificity. A negative result…
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #36 · Practice › Interactions · 17 Jul 2026 · 7 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
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Common supplements people ask about, assessed one at a time Replied, post #50 · Practice › Interactions · 15 Jul 2026 · 10 likes Anticoagulants: no direct interaction with the compounds in this class. Weight loss and body composition changes might affect the clearance or effect of warfarin if you…
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Asking a follow-up: new topic or new reply? Replied, post #50 · Start Here › How to Ask · 12 Jul 2026 · 1 like On post #46 — agreed on the reasoning, with one qualification. Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what…
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Micro-titration: a disputed topic, argued properly Replied, post #103 · Practice › Dosing & titration · 11 Jul 2026 · 0 likes When a dose reduction is the correct response to a side effect: if a side effect is dose-dependent (nausea, constipation, injection discomfort), reducing the dose is a…
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Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #26 · Clinical › Comorbidities · 11 Jul 2026 · 10 likes On post #22 — agreed on the reasoning, with one qualification. Type 2 diabetes: the population with the largest evidence base for these compounds. The SURPASS and…
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Journal club: LEADER as the historical anchor Replied, post #101 · Evidence › Journal club · 8 Jul 2026 · 0 likes SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the cardiovascular evidence to the oral formulation. Note that oral bioavailability is lower…
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Follow-up: UK access routes, dated and sourced Replied, post #10 · Regional › UK & Ireland · 8 Jul 2026 · 1 like Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
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How shortages have affected compounding permissions Replied, post #21 · Access › Shortages · 7 Jul 2026 · 7 likes On post #17 — agreed on the reasoning, with one qualification. Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking…
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Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #25 · Compounds › Retatrutide · 6 Jul 2026 · 29 likes How to read phase 2 without treating it as phase 3: phase 2 establishes that a dose range produces an effect and is tolerable enough to justify large trials. It does…
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Revisiting: Liver enzymes drifting down and what that usually means Replied, post #52 · Clinical › Bloodwork · 4 Jul 2026 · 8 likes Liver enzymes: elevation does not specify cause. ALT and AST can rise from many things. Bilirubin helps narrow down the cause. Multiple markers together are more…
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Programming during a large energy deficit Replied, post #31 · Nutrition & Training › Resistance training · 3 Jul 2026 · 0 likes Frequency: three sessions per week of full-body training is easier to maintain than higher frequencies on an energy deficit. Consistency beats intensity when recovery…