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M

MSaarinen

TL3 Regular · Santander, ES

Journal club attendee. Interested in trial design more than in trial conclusions.

Joined 31 January 2025 · last posted 4d · groups: journal-club

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  • Revisiting: Why the absence of controlled human data on BPC-157 matters more than people… Replied, post #50 · Compounds › Repair & healing peptides · 24 Jul 2026 · 30 likes This follows post #47 rather than contradicting it. What would change the position on repair peptides: adequately powered, published, peer-reviewed randomised…
  • Revisiting: Protein density versus volume when you cannot eat much Replied, post #88 · Nutrition & Training › Protein & intake · 21 Jul 2026 · 4 likes Protein sources: animal sources (meat, fish, eggs, dairy) are denser and easier to hit targets with. Plant sources require higher volume. Neither is nutritionally…
  • [2026 update] Antibiotics and a course of something with delayed emptying Replied, post #60 · Practice › Interactions · 18 Jul 2026 · 0 likes Food interactions: most interactions are absorption interactions. Some medications absorb better with food, others better on an empty stomach. With an incretin agonist…
  • Seven-day rolling means and why weekly readings mislead Replied, post #50 · Outcomes › Progress reports · 17 Jul 2026 · 0 likes Picking up post #47: that is the part I would want checked first. Menstrual cycle: for people who menstruate, weight can shift by several pounds across the cycle due to…
  • Revisiting: What pooling buys you and what it destroys Replied, post #92 · Evidence › Meta-analyses · 15 Jul 2026 · 15 likes Inclusion and exclusion criteria: a meta-analysis is only as good as its inclusion criteria. If the criteria are too broad, apples and oranges get pooled. If they are…
  • Documenting a supplier's response to a discrepancy Replied, post #33 · Sourcing › Vendor reports · 8 Jul 2026 · 17 likes Worth separating two things that post #29 runs together. Multiple services on one lot: agreement across two independent laboratories is stronger than a high number from…
  • Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #83 · Evidence › Journal club · 5 Jul 2026 · 0 likes Coming back to post #81, because the follow-up matters more than the original answer. SOUL (N Engl J Med 2025): Oral semaglutide cardiovascular outcomes. Extends the…
  • About the Adverse events category Replied, post #5 · Safety › Adverse events · 3 Jul 2026 · 2 likes Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own…
  • Request: a per-category review queue Replied, post #76 · Meta › Feature requests · 3 Jul 2026 · 6 likes Coming back to post #74, because the follow-up matters more than the original answer. Deprecation requests: if you think a feature should be removed or changed, that is…
  • Pooling trials with different estimands Replied, post #65 · Evidence › Meta-analyses · 2 Jul 2026 · 10 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
  • Second pass at: Programming during a large energy deficit Replied, post #47 · Nutrition & Training › Resistance training · 26 Jun 2026 · 5 likes Frequency: three sessions per week of full-body training is easier to maintain than higher frequencies on an energy deficit. Consistency beats intensity when recovery…
  • Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #20 · Analytics › Impurities & related substances · 24 Jun 2026 · 28 likes Coming back to post #18, because the follow-up matters more than the original answer. Acetate content: counter-ion content. Trifluoroacetate or acetate from the salt…

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