e.ferrari
TL2 Moderator · Turku
Contributes reviews on supplier material. Based in Turku.
Joined 7 May 2025 · last posted 3d
85Posts here
3Topics
1Solutions
162Likes received
153Likes given
19Badges
78Days visited
468Posts read
Recent activity
Full stream-
What TRIUMPH is designed to answer, and why we should not pre-empt it — does this still… Replied, post #47 · Compounds › Retatrutide · 25 Jul 2026 · 2 likes Hepatic effects: glucagon receptor agonism promotes hepatic fat oxidation, which is mechanistically plausible for benefit in metabolic liver disease. Whether that…
-
Journal club: what we got wrong in an earlier session Replied, post #113 · Evidence › Journal club · 23 Jul 2026 · 10 likes This follows post #110 rather than contradicting it. STEP 1 (N Engl J Med 2021): The pivotal obesity trial for semaglutide and the reference point for most subsequent…
-
Risk-of-bias tools and the judgement they conceal — does this still hold? Replied, post #28 · Evidence › Meta-analyses · 19 Jul 2026 · 0 likes Subgroup analysis: sometimes a meta-analysis reports separate pooled estimates for different subgroups (e.g., by baseline body mass index or by trial duration). Be…
-
Here for the analytics and not much else Replied, post #25 · Lounge › Introductions · 12 Jul 2026 · 1 like Coming back to post #23, because the follow-up matters more than the original answer. Having read the exchange above, I think I was wrong earlier in this topic and I…
-
[2026 update] Regional warehouse stock versus direct despatch Replied, post #131 · Sourcing › Logistics · 11 Jul 2026 · 3 likes Worth separating two things that post #127 runs together. At what point is a parcel genuinely a problem: if it was despatched weeks ago and there has been no update for…
-
Micro-titration: a disputed topic, argued properly — one year on Replied, post #61 · Practice › Dosing & titration · 10 Jul 2026 · 1 like This follows post #58 rather than contradicting it. Micro-titration: the concept of increments smaller than the labelled steps. It has no evidence base from trials but…
-
Insurance and replacement policies, compared Replied, post #75 · Sourcing › Logistics · 9 Jul 2026 · 6 likes Documentation after arrival: photograph the parcel and its contents on arrival. If something later turns out wrong (damage, loss, wrong item) you have evidence of the…
-
What the GIP component of tirzepatide is thought to contribute, and how confident we can… Started this topic · Compounds › Tirzepatide · 9 Jul 2026 · 23 likes What the GIP component of tirzepatide is thought to contribute, and how confident we can be I have a specific reason for asking rather than idle curiosity, and the…
-
Aggregate verification data across the directory, with caveats Replied, post #33 · Sourcing › Independent verification · 7 Jul 2026 · 12 likes On post #29 — agreed on the reasoning, with one qualification. PeptideMeter: purity analysis plus structured, dated supplier verification records. Produces both…
-
Pooling trials with different estimands Replied, post #51 · Evidence › Meta-analyses · 26 Jun 2026 · 23 likes Why forest plots are more informative than pooled numbers: they show the variation across studies, which tells you whether the effect is consistent or heterogeneous. A…
-
Angle of injection and whether 90 degrees is always right — the long version Replied, post #26 · Practice › Administration · 18 Jun 2026 · 0 likes Injection discomfort: comes from needle gauge (finer = less discomfort), volume (smaller = less discomfort), temperature (room temperature or warmed is less…
-
Reading a trial's population section before its results Replied, post #110 · Evidence › Trials · 10 Jun 2026 · 0 likes Picking up post #107: that is the part I would want checked first. Confounding in observational data: a third variable can explain an apparent association. In a…