f.danquah

TL2 Moderator · Mysuru

Contributes reviews on supplier material. Based in Mysuru.

Joined 7 December 2024 · last posted 4h

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How to ask about something you suspect is a bad idea — a second dataset Replied, post #3 · Start Here › How to Ask · 28 Jul 2026 · 15 likes Units. Everything needs units. This is why we ask every single time. I have seen the same arithmetic done three different ways depending on whether the person was…
Follow-up: UK access routes, dated and sourced Replied, post #15 · Regional › UK & Ireland · 26 Jul 2026 · 10 likes On post #11 — agreed on the reasoning, with one qualification. Cross-border arrangements: some people source from other EU countries. Rules on import for personal use…
Why side effects reset at each escalation and that is not a failure Replied, post #7 · Practice › Side effects · 22 Jul 2026 · 23 likes Picking up post #4: that is the part I would want checked first. Injection site reaction: local erythema, nodules, or induration at injection sites is reported by some…
How shortages have affected compounding permissions Replied, post #53 · Access › Shortages · 20 Jul 2026 · 0 likes Picking up post #50: that is the part I would want checked first. Resuming after a gap: after a gap of days or a few weeks, most people resume at the dose they were on…
[2026 update] Journal club: what we got wrong in an earlier session Replied, post #8 · Evidence › Journal club · 19 Jul 2026 · 7 likes PIONEER 6 (N Engl J Med 2019): Cardiovascular safety trial for oral semaglutide, not efficacy. Non-inferiority for safety was met. The trial was not designed to…
Seven-day rolling means and why weekly readings mislead Replied, post #53 · Outcomes › Progress reports · 18 Jul 2026 · 0 likes This follows post #50 rather than contradicting it. I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The…
What a certificate commits its issuer to Replied, post #50 · Analytics › COA interpretation · 17 Jul 2026 · 15 likes When method identifiers are missing: "reversed-phase HPLC" is less specific than "reversed-phase HPLC at 214 nm on a C18 column with a 10 to 40% acetonitrile gradient…
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #68 · Evidence › Journal club · 17 Jul 2026 · 14 likes I read post #66 twice before replying, because I had assumed the opposite. Session format: read the paper before posting. The discussion is much better when everyone…
About the Independent verification category Replied, post #3 · Sourcing › Independent verification · 16 Jul 2026 · 32 likes As a member rather than staff: the most useful thing I did when I started reading this category was to work through the tag pages rather than the topic list. The topic…
Does a peptide degrade silently, with no visual change? Replied, post #70 · Practice › Storage & stability · 14 Jul 2026 · 2 likes Temperature excursions: if a vial sat at room temperature for a time, the question is whether the excursion was long enough to cause damage. Hours at room temperature…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #96 · Evidence › Journal club · 10 Jul 2026 · 24 likes I read post #94 twice before replying, because I had assumed the opposite. SURMOUNT-OSA (N Engl J Med 2024): Tirzepatide in obstructive sleep apnoea, using an objective…
Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #25 · Analytics › Impurities & related substances · 26 Jun 2026 · 3 likes I read post #23 twice before replying, because I had assumed the opposite. Truncation products: fragments from incomplete synthesis or from degradation. They elute…