g.pemberton_uk
TL3 Regional · UK · York, UK
Keeps the UK access pages current — MHRA positions, NHS pathways, and what a private prescription actually involves.
Joined 18 September 2024 · last posted 5d · groups: wiki-editors, regional-uk
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Feature request: should a dose-equivalence tool exist at all? Started this topic · Data & Tools › Calculators · 15 Dec 2024 · 43 likes Feature request: should a dose-equivalence tool exist at all? — that is the question, and I have not found it answered plainly anywhere I have looked. Posting the…
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List price versus negotiated price versus what you pay Replied, post #112 · Access › Pricing · 17 Apr 2026 · 32 likes Worth separating two things that post #108 runs together. Cost per milligram is the only comparison that survives format differences, but even then it needs care. A pen…
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Coming back to: Why most self-reports here are not experiments, and that is fine Replied, post #46 · Research Methods › N-of-1 designs · 15 Feb 2026 · 32 likes post #45 answers the question as asked. The question underneath it is different. Objective versus subjective measures: subjective measures (how you feel) are vulnerable…
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Absence of evidence and evidence of absence Replied, post #8 · Research Methods › Statistics · 7 Dec 2025 · 32 likes Confounding: a third variable explains an apparent association. In randomised data, randomisation balances confounders. In observational data, confounders can be…
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Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #55 · Evidence › Journal club · 1 Jul 2026 · 31 likes SURMOUNT-OSA (N Engl J Med 2024): Tirzepatide in obstructive sleep apnoea, using an objective physiological endpoint. Notable because soft endpoints are avoided. Two…
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A parcel that arrived warm: a decision process, not a verdict Replied, post #46 · Practice › Storage & stability · 20 Sep 2025 · 31 likes Visual inspection: if a solution is visibly cloudy, discoloured, or contains particles, those are red flags. Faint opalescence or minor colour shift may be normal but…
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