i.aranda_es
TL2 Translator · ES · Bilbao, ES
Spanish translation for the practical pages, plus Latin American access differences.
Joined 1 November 2024 · last posted 14h · groups: translators, regional-eu
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About the N-of-1 designs category Replied, post #5 · Research Methods › N-of-1 designs · 27 Jul 2026 · 32 likes When to run an n-of-1: this design works when you want to know whether a treatment works for you, not whether it works in general. For that purpose, it is efficient.
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Pooling trials with different estimands Replied, post #103 · Evidence › Meta-analyses · 16 Jul 2026 · 19 likes Fixed-effects versus random-effects models: fixed-effects assumes all studies are estimating the same thing and variation is sampling error. Random-effects assumes…
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #106 · Compounds › Semaglutide · 15 Jul 2026 · 0 likes post #105 answers the question as asked. The question underneath it is different. The opalescent appearance in semaglutide solutions is occasionally noted and the…
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[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #32 · Practice › Interactions · 11 Jul 2026 · 0 likes Food interactions: most interactions are absorption interactions. Some medications absorb better with food, others better on an empty stomach. With an incretin agonist…
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Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #36 · Pharmacology › Receptor biology · 5 Jul 2026 · 0 likes Glucagon receptor agonism: glucagon receptor agonism increases energy expenditure and promotes hepatic fat oxidation. The mechanism is distinct from GLP-1 and GIP…
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Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #76 · Analytics › Method validation · 3 Jul 2026 · 1 like Limits of detection and quantitation: LOD is the lowest concentration that produces a signal above background. LOQ is the lowest concentration at which the method meets…
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What a reversed-phase purity number actually is Replied, post #16 · Analytics › HPLC & UHPLC · 1 Jul 2026 · 9 likes Reversed-phase separates on hydrophobicity. A peptide is retained on a non-polar stationary phase and eluted by increasing organic solvent. For peptides the mobile…
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Personal or family history of medullary thyroid carcinoma Replied, post #17 · Safety › Contraindications · 26 Jun 2026 · 0 likes Diabetic retinopathy complications: a signal for this was noted in SUSTAIN 6. Current evidence is mixed. The risk is not zero and some caution is appropriate in people…
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[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #17 · Access › International · 15 Jun 2026 · 9 likes Compounding in different countries: some countries allow pharmacy compounding under defined conditions; others do not. The rules are jurisdiction-specific and change.
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Follow-up: Reading an interaction checker output critically Replied, post #6 · Practice › Interactions · 15 Jun 2026 · 0 likes Picking up post #3: that is the part I would want checked first. Anticoagulants: no direct interaction with the compounds in this class. Weight loss and body…
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What I would want from a home test that does not exist yet — what changed since Replied, post #53 · Analytics › Home & field testing · 13 Jun 2026 · 15 likes Lateral-flow devices: like a rapid COVID test. They have a reagent strip and produce a colour result. They are quick but not precise and not intended for quantitative…
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Coming back to: Why a preprint's supplementary material is often the best part Replied, post #77 · Evidence › Preprints · 12 Jun 2026 · 0 likes I read post #75 twice before replying, because I had assumed the opposite. Preprints for speed: some important preliminary findings are posted as preprints to…