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Evidence · Preprints · continued

Coming back to: Why a preprint's supplementary material is often the best part posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

FL
f.lindholmTL2 Moderator24 May 2026 · edited#61

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

4 likes 2mo
IL
integrator_logTL3Regular25 May 2026#62
f.lindholm, post #61: Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim. Go to post

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

12 likes in reply to #61 2mo
BF
b.friskTL2 Moderator27 May 2026#63
KLindqvist, post #20: This follows post #17 rather than contradicting it. What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

post #62 answers the question as asked. The question underneath it is different.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

0 likes in reply to #20 2mo
BS
buffer_sheetTL3Regular28 May 2026#64

On post #60 — agreed on the reasoning, with one qualification.

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

0 likes 2mo
IW
i.wojcikTL2 Moderator29 May 2026#65

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

1 like 2mo
BE
bench_entryTL3Regular30 May 2026#66
preregistered, post #58: post #57 is right about the mechanism and I think understates the practical bit. Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised. Go to post

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

7 likes in reply to #58 2mo
JF
j.falkTL2 Moderator31 May 2026#67

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

25 likes 2mo
V
VPoulsenTL3Regular2 Jun 2026#68

Worth separating two things that post #64 runs together.

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

0 likes 2mo
KA
k.asanteTL2 Moderator3 Jun 2026#69

Picking up post #66: that is the part I would want checked first.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

11 likes 2mo
CC
crossref_checkTL3Wiki editor4 Jun 2026#70

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

24 likes 2mo
FN
formulary_notesTL3Regular5 Jun 2026#71

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

10 likes 2mo
CA
c.amankwahTL2 Moderator6 Jun 2026#72

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

3 likes 2mo
SC
s.chowdhuryTL3Regular8 Jun 2026#73

Coming back to post #71, because the follow-up matters more than the original answer.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes 2mo
AI
an.ibarraTL2 Moderator9 Jun 2026#74
b.frisk, post #63: post #62 answers the question as asked. The question underneath it is different. What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

Picking up post #71: that is the part I would want checked first.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

23 likes in reply to #63 2mo
SL
sleep_logTL2Regular10 Jun 2026#75
n.vukovic, post #55: I read post #53 twice before replying, because I had assumed the opposite. How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint. Go to post

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

15 likes in reply to #55 2mo
LV
l.vukovicTL2 Moderator11 Jun 2026#76

post #75 is right about the mechanism and I think understates the practical bit.

I disagree with the reply above, and I think the disagreement is substantive rather than terminological.

The distinction being drawn does not survive when you look at the published data for this specific question. I would be glad to be shown wrong on this, because the version I am arguing against is more convenient.

6 likes 2mo
IA
i.aranda_esTL2Translator · ES12 Jun 2026 · edited#77

I read post #75 twice before replying, because I had assumed the opposite.

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

0 likes 2mo
II
i.ilungaTL2 Moderator13 Jun 2026#78

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

31 likes 1mo
SG
s.grigorescuTL2Member14 Jun 2026#79

On post #75 — agreed on the reasoning, with one qualification.

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

22 likes 1mo
SR
sa.rasmussenTL2 Moderator16 Jun 2026#80

post #79 answers the question as asked. The question underneath it is different.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

10 likes 1mo
RB
r.bakkenTL2 Moderator17 Jun 2026#81

post #80 answers the question as asked. The question underneath it is different.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

13 likes 1mo
NR
n.rowntreeTL3Regular18 Jun 2026#82
bench_entry, post #66: Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

On post #78 — agreed on the reasoning, with one qualification.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

27 likes in reply to #66 1mo
KK
k.kuuselaTL2 Moderator19 Jun 2026#83

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

0 likes 1mo
FE
footnote_entryTL3Regular20 Jun 2026#84

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

2 likes 1mo
JR
j.restrepoTL2 Moderator21 Jun 2026#85

post #84 is right about the mechanism and I think understates the practical bit.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

19 likes 1mo
K
KAnderssonTL3Regular22 Jun 2026 · edited#86
i.ilunga, post #78: Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions. Go to post

Worth separating two things that post #82 runs together.

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

0 likes in reply to #78 1mo
EF
e.ferreiraTL324 Jun 2026#87
CW
c.wijnbergTL2Member25 Jun 2026#88

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

5 likes 1mo
IG
i.guerreroTL2 Moderator26 Jun 2026#89

post #88 answers the question as asked. The question underneath it is different.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

5 likes 1mo
BW
bac_waterTL2Regular27 Jun 2026#90

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

14 likes 1mo