k.otieno_stats
TL3 Statistician · Kisumu, KE
Applied statistician. Effect sizes, confidence intervals, and the difference between "no difference" and "not powered to detect one".
Joined 12 September 2024 · last posted 6d · groups: journal-club
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Revisiting: The best-written scientific paper you have read Replied, post #109 · Lounge › Off topic · 22 Jul 2026 · 0 likes On post #105 — agreed on the reasoning, with one qualification. Two things before anyone answers the substance. First, the context in the first post is clear and…
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Revisiting: PCOS and metabolic overlap: what is and is not studied Replied, post #58 · Clinical › Comorbidities · 22 Jul 2026 · 1 like Worth separating two things that post #54 runs together. Bariatric surgery history: altered anatomy after surgery affects absorption. That matters for oral medications…
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[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #55 · Analytics › HPLC & UHPLC · 21 Jul 2026 · 11 likes Picking up post #52: that is the part I would want checked first. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the…
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Prior authorisation: what the criteria usually require — a second dataset Replied, post #45 · Access › Insurance & coverage · 19 Jul 2026 · 26 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
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Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #39 · Compounds › Retatrutide · 19 Jul 2026 · 22 likes post #38 is right about the mechanism and I think understates the practical bit. Why this subcategory is more cautious than elsewhere: retatrutide is investigational,…
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A pooled estimate that changed when one trial was added Replied, post #25 · Evidence › Meta-analyses · 18 Jul 2026 · 15 likes Sensitivity analysis: the authors re-run the meta-analysis excluding studies one at a time, or by quality, to see whether the pooled estimate changes. Robust results…
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[2026 update] Currency conversion and the cost you did not see Replied, post #26 · Sourcing › Payments · 18 Jul 2026 · 0 likes Coming back to post #24, because the follow-up matters more than the original answer. Bank transfer and finality: once a bank transfer is sent, it is final. The money…
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What a certificate commits its issuer to Replied, post #38 · Analytics › COA interpretation · 15 Jul 2026 · 6 likes Counter-ion form is crucial: peptides are isolated as salts, most often trifluoroacetate from reversed-phase purification or acetate after salt exchange. The…
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Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #59 · Compounds › Retatrutide · 13 Jul 2026 · 0 likes Triple agonism: is the effect additive, synergistic, or neither? A phase 2 comparison of tirzepatide (dual) to retatrutide (triple) would answer that question. The…
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Follow-up: Signs of dehydration worth acting on Replied, post #23 · Safety › Adverse events · 13 Jul 2026 · 9 likes Medullary thyroid carcinoma is the reason these compounds are contraindicated in people with personal or family history of MTC or multiple endocrine neoplasia type 2.…
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The anatomy of a question that gets answered within an hour Replied, post #106 · Start Here › How to Ask · 9 Jul 2026 · 0 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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What I would want from a home test that does not exist yet Replied, post #28 · Analytics › Home & field testing · 5 Jul 2026 · 16 likes What physical quantity does the device measure? A colorimetric or lateral-flow method typically responds to a class of chemistry rather than to a specific molecule. It…