m.guerrero
TL2 Moderator · Plovdiv
Contributes reviews on supplier material. Based in Plovdiv.
Joined 1 May 2025 · last posted 4d · groups: regional-apac, newcomer-guides
93Posts here
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Revisiting: PCOS and metabolic overlap: what is and is not studied Replied, post #59 · Clinical › Comorbidities · 24 Jul 2026 · 7 likes Hepatic steatosis and MASH: a phase 2 trial in semaglutide for steatohepatitis showed resolution was more frequent on treatment. Histological resolution is a surrogate…
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Angle of injection and whether 90 degrees is always right — the long version Replied, post #48 · Practice › Administration · 17 Jul 2026 · 5 likes Bleeding at the injection site: normal and usually minimal. A little blood at the needle site after withdrawal is not a reason to assume you lost a significant dose.…
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Why a glucagon receptor agonist in a weight-loss compound is not a contradiction Replied, post #36 · Compounds › Retatrutide · 16 Jul 2026 · 17 likes On post #32 — agreed on the reasoning, with one qualification. Glucagon receptor agonism seems paradoxical in a weight-loss compound because glucagon raises blood…
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Journal club: what we got wrong in an earlier session Replied, post #76 · Evidence › Journal club · 12 Jul 2026 · 3 likes SURPASS-2 (N Engl J Med 2021): Direct comparison of tirzepatide with semaglutide 1.0 mg. The 1.0 mg dose is not the highest available, which is the central and…
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How shortages have affected compounding permissions Replied, post #32 · Access › Shortages · 12 Jul 2026 · 26 likes Coming back to post #30, because the follow-up matters more than the original answer. Managing an unplanned gap: if a shortage causes a gap in treatment, the questions…
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Follow-up: Reading an interaction checker output critically Replied, post #41 · Practice › Interactions · 11 Jul 2026 · 13 likes On post #37 — agreed on the reasoning, with one qualification. Two things before anyone answers the substance. First, the context in the first post is clear and…
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Spreadsheets: an appreciation — what changed since Replied, post #95 · Lounge › Off topic · 9 Jul 2026 · 3 likes This follows post #92 rather than contradicting it. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still…
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Reflectance and photometric devices: precision in practice — a second dataset Replied, post #67 · Analytics › Home & field testing · 7 Jul 2026 · 2 likes On post #63 — agreed on the reasoning, with one qualification. Enzyme assays: if you have an enzyme that reacts specifically with your compound, an enzyme-based assay…
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Follow-up: Comparing two chromatograms from different laboratories, properly Replied, post #51 · Analytics › HPLC & UHPLC · 29 Jun 2026 · 16 likes Peak purity: a diode-array detector records a spectrum at every time point. If a peak contains two co-eluting species with different spectra, the spectrum changes…
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Revisiting: The best-written scientific paper you have read Replied, post #51 · Lounge › Off topic · 25 Jun 2026 · 22 likes I read post #49 twice before replying, because I had assumed the opposite. Science communication: if you come across an interesting science paper or article about…
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Second pass at: Which categories are strict and which are relaxed, honestly Replied, post #77 · Start Here › Welcome · 18 Jun 2026 · 0 likes Nothing here requires expertise. The experienced members here got that way by posting questions, not by knowing the answer before they showed up. If you know something…
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Racemisation and why it is invisible to a mass measurement Replied, post #90 · Analytics › Impurities & related substances · 13 Jun 2026 · 0 likes Off-target structures: if the sequence synthesis goes wrong, a completely different amino acid can be incorporated. The resulting off-target peptide is a structural…