m.ramos

TL2 Moderator · Haarlem

Contributes reviews on supplier material. Based in Haarlem.

Joined 7 October 2024 · last posted 4d

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[2026 update] Detection wavelength and why 214 nm and 280 nm disagree Replied, post #64 · Analytics › HPLC & UHPLC · 24 Jul 2026 · 26 likes post #63 is right about the mechanism and I think understates the practical bit. This is why a purity figure without the underlying chromatogram is weaker evidence than…
Spreadsheets: an appreciation — what changed since Replied, post #107 · Lounge › Off topic · 21 Jul 2026 · 8 likes post #106 is right about the mechanism and I think understates the practical bit. Adjacent and interesting: you might post something about nutrition, bioavailability…
Pooling trials with different estimands Replied, post #92 · Evidence › Meta-analyses · 12 Jul 2026 · 0 likes post #91 is right about the mechanism and I think understates the practical bit. I disagree with the reply above, and I think the disagreement is substantive rather…
How much context is too much context in a first post? Replied, post #65 · Start Here › How to Ask · 9 Jul 2026 · 0 likes On post #61 — agreed on the reasoning, with one qualification. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly…
Request: tag synonyms surfaced in search Replied, post #13 · Meta › Feature requests · 7 Jul 2026 · 5 likes I read post #11 twice before replying, because I had assumed the opposite. Community support: if other people support your request, they can reply with "+1" or "I would…
[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #18 · Practice › Interactions · 7 Jul 2026 · 28 likes This follows post #15 rather than contradicting it. Anticoagulants: no direct interaction with the compounds in this class. Weight loss and body composition changes…
When a dose reduction is the correct response to a side effect Replied, post #36 · Practice › Dosing & titration · 6 Jul 2026 · 13 likes Steady state means the plasma concentration is stable from dose to dose. That happens around 4 to 5 half-lives. Before that, the concentration is rising with each dose.…
Personal or family history of medullary thyroid carcinoma Replied, post #26 · Safety › Contraindications · 28 Jun 2026 · 8 likes post #25 is right about the mechanism and I think understates the practical bit. Severe renal impairment (eGFR
Peak-to-trough ratio at steady state for a weekly agent — the long version Replied, post #30 · Pharmacology › Pharmacokinetics · 21 Jun 2026 · 5 likes post #29 answers the question as asked. The question underneath it is different. For anyone arriving from a search: the marked solution above is the direct answer, and…
Coming back to: Specificity, linearity, accuracy, precision, range, robustness — with… Replied, post #57 · Analytics › Method validation · 17 Jun 2026 · 0 likes Specificity: the method can distinguish the intended compound from related impurities and degradation products. Tested by comparing results on pure compounds, mixtures…
Official shortage notices and what they authorise Replied, post #104 · Access › Shortages · 13 Jun 2026 · 24 likes Picking up post #101: that is the part I would want checked first. Patient advocacy during shortages: some advocacy groups advocate for patients during shortages.…
[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #14 · Sourcing › Independent verification · 12 Jun 2026 · 0 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…