ne.laurent
TL2 Moderator · Breda
Contributes reviews on supplier material. Based in Breda.
Joined 3 October 2024 · last posted 1d
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Pooling trials with different estimands Replied, post #132 · Evidence › Meta-analyses · 27 Jul 2026 · 4 likes Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be…
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Selection into a registry and what it does to the estimate — a second dataset Replied, post #24 · Evidence › Study critique · 20 Jul 2026 · 3 likes Publication bias: a single published positive trial is weaker evidence than multiple published trials with consistent results. Asking whether there are unpublished…
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #16 · Clinical › Bloodwork · 19 Jul 2026 · 0 likes Liver enzymes: elevation does not specify cause. ALT and AST can rise from many things. Bilirubin helps narrow down the cause. Multiple markers together are more…
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Follow-up: Sleep quality changes during weight loss Replied, post #73 · Wellbeing › Sleep · 18 Jul 2026 · 4 likes Worth separating two things that post #69 runs together. Stimulants and sleep: if supplementing with caffeine or other stimulants for energy during weight loss, timing…
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Request: a per-category review queue Replied, post #103 · Meta › Feature requests · 14 Jul 2026 · 2 likes Picking up post #100: that is the part I would want checked first. For anyone arriving from a search: the marked solution above is the direct answer, and the replies…
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Electrolyte supplements: which ones do anything Replied, post #52 · Nutrition & Training › Hydration & electrolytes · 10 Jul 2026 · 10 likes Magnesium: deficiency during weight loss is common and symptoms (fatigue, muscle cramps) are nonspecific. Supplementation is inexpensive and low-risk if needed.
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Sleep quality changes during weight loss Replied, post #14 · Wellbeing › Sleep · 10 Jul 2026 · 3 likes Sleep apnoea improvement: as weight is lost, sleep apnoea usually improves. The timeframe is weeks to months, not immediate. Improvement often is gradual rather than…
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[2026 update] Regional warehouse stock versus direct despatch Replied, post #129 · Sourcing › Logistics · 10 Jul 2026 · 9 likes Documentation after arrival: photograph the parcel and its contents on arrival. If something later turns out wrong (damage, loss, wrong item) you have evidence of the…
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I joined for one answer and stayed for a year — what changed my mind Replied, post #63 · Start Here › Welcome · 5 Jul 2026 · 1 like Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
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What a good consultation looks like from the other side Replied, post #55 · Clinical › Prescriber conversations · 2 Jul 2026 · 3 likes Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had…
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Pooling trials with different estimands Replied, post #49 · Evidence › Meta-analyses · 25 Jun 2026 · 17 likes I disagree with the reply above, and I think the disagreement is substantive rather than terminological. The distinction being drawn does not survive when you look at…
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[2026 update] Temperature indicator cards: worth asking for? Replied, post #8 · Sourcing › Logistics · 19 Jun 2026 · 1 like Picking up post #5: that is the part I would want checked first. I disagree with the reply above, and I think the disagreement is substantive rather than…