s.duarte
TL2 Moderator · Faro
Contributes reviews on supplier material. Based in Faro.
Joined 30 March 2025 · last posted 1d
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About the Shortages category Replied, post #8 · Access › Shortages · 26 Jul 2026 · 0 likes Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and…
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Immortal time bias in a claims-database study — one year on Replied, post #44 · Evidence › Study critique · 25 Jul 2026 · 19 likes I read post #42 twice before replying, because I had assumed the opposite. Bias towards the null and bias away from the null: different criticisms have different…
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Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #90 · Compounds › Retatrutide · 24 Jul 2026 · 0 likes Retatrutide is investigational. Anything obtained outside a trial is by definition research-use-only material with no human-use authorisation. This site will state that…
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[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #100 · Access › International · 22 Jul 2026 · 2 likes Compounding in different countries: some countries allow pharmacy compounding under defined conditions; others do not. The rules are jurisdiction-specific and change.
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What to include when your question involves a chromatogram — one year on Replied, post #76 · Start Here › How to Ask · 14 Jul 2026 · 8 likes Avoid "any advice?" at the end. It is so generic that people do not know which part of the post it refers to. Pick the specific part and ask that specific question…
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Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #11 · Clinical › Comorbidities · 9 Jul 2026 · 30 likes Type 2 diabetes: the population with the largest evidence base for these compounds. The SURPASS and SUSTAIN programmes established glycaemic benefit. The renal and…
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Sleep apnoea improving and the equipment implications Replied, post #5 · Wellbeing › Sleep · 12 Jun 2026 · 0 likes Sleep apnoea improvement: as weight is lost, sleep apnoea usually improves. The timeframe is weeks to months, not immediate. Improvement often is gradual rather than…
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Preservatives: function, testing, and limits — one year on Replied, post #22 · Pharmacology › Formulation chemistry · 7 Jun 2026 · 0 likes Excipients and their purposes: mannitol, sucrose, or other sugars in lyophilised formulations protect the peptide during drying and storage. They are not impurities;…
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Tracking a shortage from primary sources rather than rumour Replied, post #39 · Access › Shortages · 6 Jun 2026 · 9 likes Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and…
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Comparing prices across jurisdictions without misleading yourself Replied, post #20 · Access › Pricing · 30 May 2026 · 0 likes Compute cost per delivered dose at your dose if you want a number you can act on. That requires knowing your dose, vial volume, and whether you are using a vial or a pen.
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Why fasting instructions for oral semaglutide are not optional advice Replied, post #8 · Compounds › Oral incretins · 19 May 2026 · 3 likes Picking up post #5: that is the part I would want checked first. The SOUL trial: cardiovascular outcomes trial for oral semaglutide in people with type 2 diabetes and…
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #32 · Compounds › Semaglutide · 19 May 2026 · 0 likes post #31 is right about the mechanism and I think understates the practical bit. Albumin binding is not a unique structural feature and nothing in the class lacks it,…