s.poulsen
TL3 Regular · Ljubljana, SI
Clinician. Posts general information only, and says so every time.
Joined 26 August 2024 · last posted 2d · groups: clinicians
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About the Adverse events category Replied, post #7 · Safety › Adverse events · 26 Jul 2026 · 28 likes Worth separating two things that post #3 runs together. Serious and unexpected events are the ones to document and report. Serious means hospitalization-level serious.…
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #63 · Practice › Interactions · 24 Jul 2026 · 0 likes Metformin: commonly co-administered and relevant to gastrointestinal tolerability. Gastrointestinal side effects can overlap and additive. Taking them separately or…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #83 · Practice › Dosing & titration · 21 Jul 2026 · 1 like The four-week escalation interval is a convention from the pivotal trials, not a pharmacological constant. The pharmacological argument is that with a week-long…
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #82 · Nutrition & Training › Protein & intake · 19 Jul 2026 · 25 likes Protein supplements: whey, casein, and plant-based protein powders can help hit targets when whole-food intake is limited by appetite. Protein quality (all essential…
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What consumer-accessible tests can and cannot determine — a second dataset Replied, post #96 · Analytics › Home & field testing · 17 Jul 2026 · 10 likes Immunoassay limitations: tests that use antibodies have cross-reactivity limitations. An antibody raised to semaglutide will cross-react to some degree with tirzepatide…
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Coming back to: Delayed gastric emptying and oral medication absorption: which drugs… Replied, post #7 · Practice › Interactions · 8 Jul 2026 · 23 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
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Prescription requirements and telehealth models — a second dataset Replied, post #93 · Sourcing › Regulatory · 6 Jul 2026 · 14 likes Off-label use and medical practice: clinicians can prescribe approved medications off-label under some circumstances. That is different from research-use-only…
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Naming conventions for research peptides and the confusion they cause Replied, post #23 · Compounds › Other compounds · 30 Jun 2026 · 1 like post #22 answers the question as asked. The question underneath it is different. When "no data" is the complete and final answer: if there is no published human data on…
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Documenting a supplier's response to a discrepancy Replied, post #22 · Sourcing › Vendor reports · 24 Jun 2026 · 8 likes Temporal patterns: if results from a supplier were good two years ago but have deteriorated recently, that is information. If they have been consistent over years, that…
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Historical amylin analogues and what happened to them Replied, post #23 · Compounds › Cagrilintide & amylin analogues · 24 Jun 2026 · 1 like Cagrilintide alone is discussed less than in combination because the published data is almost entirely from combination trials. The phase 2 combination data was…
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GLP-1 receptor distribution: central and peripheral Replied, post #74 · Pharmacology › Receptor biology · 21 Jun 2026 · 1 like Pharmacological class effects: all GLP-1 agonists slow gastric emptying and suppress appetite. Those are class effects, not unique to one compound. Effects that differ…
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Packaging that arrived damaged: documenting it properly Replied, post #27 · Sourcing › Logistics · 18 Jun 2026 · 9 likes Packaging integrity on arrival: if a parcel arrives with compromised packaging, that is evidence of a handling problem in transit. The contents may or may not be…