taper_shift
TL3 Regular · Nijmegen, NL
Journal club attendee. Interested in trial design more than in trial conclusions.
Joined 10 August 2024 · last posted 10d · groups: journal-club
111Posts here
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Most-liked posts
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Time to steady state after a dose increase Replied, post #59 · Pharmacology › Pharmacokinetics · 4 Nov 2024 · 33 likes On post #55 — agreed on the reasoning, with one qualification. Half-life: semaglutide ≈ 165–184 hours (about a week). Tirzepatide ≈ 5 days. Liraglutide ≈ 13 hours. The…
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How to ask for a dose change without antagonising anyone Replied, post #10 · Clinical › Prescriber conversations · 31 Jul 2024 · 33 likes Prescription logistics: confirm whether it will be filled locally, requires mail order, or will be prescribed off-label and needs a compounding pharmacy. Different…
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Why "any advice?" is the least effective ending for a post — the long version Replied, post #70 · Start Here › How to Ask · 16 Oct 2025 · 32 likes Units. Everything needs units. This is why we ask every single time. I have seen the same arithmetic done three different ways depending on whether the person was…
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Follow-up: Tracking intake honestly when appetite is absent Replied, post #43 · Nutrition & Training › Protein & intake · 8 Jun 2025 · 32 likes Fibre: adequate fibre intake supports fullness and gut motility, both of which matter during the gastrointestinal effects of these compounds. High fibre on top of…
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Obstructive sleep apnoea and a hard endpoint in this class Replied, post #26 · Clinical › Comorbidities · 4 Mar 2025 · 32 likes Interactions between comorbidities: diabetes and kidney disease together change the risk calculation for hypoglycemia and for medication clearance. They are not…
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Guidelines revision: what changed and why — does this still hold? Replied, post #3 · Meta › Announcements · 10 Jan 2026 · 31 likes When announcements are made: major policy changes, technical changes affecting site function, planned downtime, and changes to guidelines all get announced here.
Where this member posts
Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| Basic User | bronze | 12 Aug 2024 |
| Read the Guidelines | bronze | 12 Aug 2024 |
| Welcome | bronze | 15 Aug 2024 |
| First Reply | bronze | 17 Aug 2024 |
| First Topic | bronze | 17 Aug 2024 |
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| First Link | bronze | 31 Aug 2024 |
| First Quote | bronze | 2 Sep 2024 |
| Journal Club | bronze | 6 Sep 2024 |
| First Tag | bronze | 9 Sep 2024 |
| Member | bronze | 19 Sep 2024 |
| Sourced | bronze | 27 Sep 2024 |
| Editor | bronze | 12 Oct 2024 |
| Reader | bronze | 6 Nov 2024 |
| Good Post | silver | 14 Nov 2024 |
| Read the Protocol | silver | 28 Nov 2024 |
| Consistently Generous | silver | 1 Dec 2024 |
| First Solution | bronze | 11 Dec 2024 |
| Popular Link | silver | 31 Dec 2024 |
| Nice Topic | bronze | 3 Jan 2025 |
| Nice Post | bronze | 5 Jan 2025 |
| Thank You | silver | 23 Feb 2025 |
| Journal Club Regular | silver | 7 Mar 2025 |
| Documented a Red Flag | silver | 7 Mar 2025 |
| Regular | silver | 20 Mar 2025 |
| Gives Back | gold | 3 Apr 2025 |
| Absolute Numbers | silver | 9 Apr 2025 |
| First Vendor Report | bronze | 25 Apr 2025 |
| Changed My Mind | silver | 22 May 2025 |
| Well Sourced | silver | 25 Jul 2025 |
| Anniversary | silver | 10 Aug 2025 |