taper_shift
TL3 Regular · Nijmegen, NL
Journal club attendee. Interested in trial design more than in trial conclusions.
Joined 10 August 2024 · last posted 10d · groups: journal-club
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Prior authorisation: what the criteria usually require — a second dataset Replied, post #40 · Access › Insurance & coverage · 18 Jul 2026 · 9 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
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Restarting after a long gap: what the labelling implies Replied, post #28 · Practice › Dosing & titration · 16 Jul 2026 · 1 like Worth separating two things that post #24 runs together. Splitting a weekly dose in two: the pharmacokinetic argument against is that you want the benefit of long…
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #105 · Evidence › Journal club · 14 Jul 2026 · 26 likes SURMOUNT-1 (N Engl J Med 2022): Tirzepatide obesity trial. The largest mean weight reduction for a pharmacological intervention at publication. Read the categorical…
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Prior authorisation: what the criteria usually require — a second dataset Replied, post #25 · Access › Insurance & coverage · 13 Jul 2026 · 11 likes Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the…
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Insurance and replacement policies, compared Replied, post #85 · Sourcing › Logistics · 13 Jul 2026 · 24 likes Import restrictions by jurisdiction: what is legal to import for personal use varies enormously by country. Some jurisdictions are quite permissive; others are not.…
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Reflectance and photometric devices: precision in practice — a second dataset Replied, post #70 · Analytics › Home & field testing · 11 Jul 2026 · 2 likes This follows post #67 rather than contradicting it. Why third-party testing is stronger: a home test run by the person who made the compound is a self-selected result.…
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Follow-up: Signs of dehydration worth acting on Replied, post #18 · Safety › Adverse events · 8 Jul 2026 · 15 likes post #17 answers the question as asked. The question underneath it is different. Acute kidney injury: rare but reported. Symptoms (decreased urine output, creatinine…
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Second pass at: The storage lookup and where its data comes from Replied, post #39 · Data & Tools › Calculators · 1 Jul 2026 · 4 likes I read post #37 twice before replying, because I had assumed the opposite. Reporting bugs: if you notice a calculator giving wrong results, report it in this…
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Second pass at: Cost versus information: making the trade-off explicitly Replied, post #14 · Analytics › Home & field testing · 1 Jul 2026 · 0 likes post #13 is right about the mechanism and I think understates the practical bit. Enzyme assays: if you have an enzyme that reacts specifically with your compound, an…
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Reading a home test result without over-claiming Replied, post #100 · Analytics › Home & field testing · 30 Jun 2026 · 16 likes Precision of home tests: most consumer-accessible devices are not precise to the level people want ("is this 99% pure or 97% pure"). They give a yes/no or a rough…
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #18 · Nutrition & Training › Protein & intake · 29 Jun 2026 · 13 likes I read post #16 twice before replying, because I had assumed the opposite. Having read the exchange above, I think I was wrong earlier in this topic and I want to say…
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #38 · Access › Insurance & coverage · 25 Jun 2026 · 0 likes Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…