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Devices · Syringes & needles · continued

Fixed versus detachable needles: the trade-offs posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

SG
s.grahameTL2Member20 Dec 2024#61

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

13 likes 19mo
RI
r.ilungaTL2 Moderator21 Dec 2024#62
Ziegler, post #41: post #40 is right about the mechanism and I think understates the practical bit. Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity. Go to post

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

27 likes in reply to #41 19mo
BS
buffer_sheetTL3Regular21 Dec 2024#63
r.ilunga, post #62: Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less. Go to post

post #62 answers the question as asked. The question underneath it is different.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

0 likes in reply to #62 19mo
ER
e.roosTL2 Moderator22 Dec 2024#64

On post #60 — agreed on the reasoning, with one qualification.

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

5 likes 19mo
BE
bench_entryTL3Regular22 Dec 2024#65

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

9 likes 19mo
BW
b.wikstromTL2 Moderator23 Dec 2024#66
TL4_Halvorsen, post #37: Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

20 likes in reply to #37 19mo
BJ
b.jankowiakTL3Regular23 Dec 2024#67

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

0 likes 19mo
PD
p.dialloTL2 Moderator24 Dec 2024 · edited#68

Worth separating two things that post #64 runs together.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

2 likes 19mo
O
OTeixeiraTL3Regular24 Dec 2024#69
m.stephanopoulos, post #45: post #44 answers the question as asked. The question underneath it is different. Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less. Go to post

Picking up post #66: that is the part I would want checked first.

For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.

5 likes in reply to #45 19mo
FI
f.ibarraTL2 Moderator25 Dec 2024#70
s.grahame, post #61: Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters. Go to post

Coming back to post #68, because the follow-up matters more than the original answer.

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

14 likes in reply to #61 19mo
AW
a.westergaardTL3Regular25 Dec 2024 · edited#71

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

8 likes 19mo
CF
c.falkTL2 Moderator26 Dec 2024#72
k.vanhecke, post #7: Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up. Go to post

post #71 answers the question as asked. The question underneath it is different.

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

2 likes in reply to #7 19mo
ZL
z.laurentTL2 Moderator26 Dec 2024#73

Coming back to post #71, because the follow-up matters more than the original answer.

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

0 likes 19mo
DY
d.yilmazTL2 Moderator27 Dec 2024#74

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

19 likes 19mo
CL
c.lundgrenTL2 Moderator27 Dec 2024#75

Worth separating two things that post #71 runs together.

Practical note that does not fit anywhere else. Whatever you conclude from this topic, write down what you did and when. The single most useful thing in your own records is not any individual result; it is that they are dated and consecutive.

12 likes 19mo
HE
h.eriksenTL2 Moderator28 Dec 2024#76
ni.kravchenko, post #15: Coming back to post #13, because the follow-up matters more than the original answer. Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers. Go to post

post #75 is right about the mechanism and I think understates the practical bit.

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

4 likes in reply to #15 19mo
ML
m.lehtinenTL2 Moderator28 Dec 2024#77
b.jankowiak, post #67: Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses. Go to post

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

0 likes in reply to #67 19mo
NN
n.nybergTL2 Moderator29 Dec 2024#78

Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses.

26 likes 19mo
BT
baseline_tableTL2Member29 Dec 2024#79

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

2 likes 19mo
EK
ew.kuuselaTL2 Moderator30 Dec 2024#80

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

0 likes 19mo
NL
n.laurentTL2 Moderator30 Dec 2024#81

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

6 likes 19mo
CR
compounding_ruthTL4Pharmacist31 Dec 2024#82
a.zamora, post #49: For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use. Go to post

On post #78 — agreed on the reasoning, with one qualification.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

16 likes in reply to #49 19mo
HD
h.delgadoTL2 Moderator31 Dec 2024#83

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

31 likes 19mo
IT
impurity_tableTL31 Jan 2025#84
SD
s.dziedzicTL2 Moderator1 Jan 2025#85
Ziegler, post #41: post #40 is right about the mechanism and I think understates the practical bit. Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity. Go to post

post #84 is right about the mechanism and I think understates the practical bit.

Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error.

10 likes in reply to #41 19mo
SC
so.cardosoTL2 Moderator2 Jan 2025#86
s.grahame, post #61: Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters. Go to post

Worth separating two things that post #82 runs together.

Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice.

22 likes in reply to #61 19mo
VS
v.sjobergTL2 Moderator2 Jan 2025#87

Sharps disposal: needles and syringes should be disposed in a sharps container (a rigid, puncture-resistant container). Do not put them in regular trash. Many pharmacies accept filled sharps containers.

0 likes 19mo
TV
t.vasquezTL4 Moderator3 Jan 2025 · edited#88

Insulin syringe graduations: U-100 syringes are marked in units where 100 units = 1 mL. Always confirm your syringe is U-100. Confusion between insulin units and milligrams is the most common syringe error.

1 like 19mo
AI
a.iyerTL2 Moderator3 Jan 2025#89
isotonic_sheet, post #16: Picking up post #13: that is the part I would want checked first. Aspirating before injection: for subcutaneous injection, aspirating (pulling back on the plunger to check for blood) is not necessary and is sometimes discouraged because it is associated with more discomfort. Subcutaneous injection without aspiration is standard practice. Go to post

Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.

15 likes in reply to #16 19mo
RM
r.mcalisterTL3Regular4 Jan 2025#90
y.adebayo, post #36: Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose. Go to post

Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.

30 likes in reply to #36 19mo