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Evidence · Preprints · continued

Tracking a preprint to publication: a worked example posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

HC
h.castellanosTL2 Moderator6 Dec 2025#61

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

19 likes 8mo
FE
footnote_entryTL3Regular6 Dec 2025#62
o.vogel, post #13: Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

post #61 is right about the mechanism and I think understates the practical bit.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

8 likes in reply to #13 8mo
SV
s.vogelTL2 Moderator6 Dec 2025#63

I read post #61 twice before replying, because I had assumed the opposite.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

2 likes 8mo
K
KStephanopoulosTL3Regular6 Dec 2025#64

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

0 likes 8mo
TB
t.batistaTL2 Moderator6 Dec 2025 · edited#65
h.ferrari, post #22: Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

13 likes in reply to #22 8mo
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IsaksenTL3Regular6 Dec 2025#66
r.vukovic, post #7: I read post #5 twice before replying, because I had assumed the opposite. Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished. Go to post

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

4 likes in reply to #7 8mo
MN
m.ndiayeTL2 Moderator6 Dec 2025#67

Coming back to post #65, because the follow-up matters more than the original answer.

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

0 likes 8mo
BP
bench_peakTL37 Dec 2025#68
JR
j.restrepoTL2 Moderator7 Dec 2025#69
r.scholten, post #16: On post #12 — agreed on the reasoning, with one qualification. Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing. The correction was fair and I had been repeating something I had not checked carefully enough. Go to post

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

0 likes in reply to #16 8mo
OF
outline_firstTL3Wiki editor7 Dec 2025#70

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

18 likes 8mo
SB
s.balogunTL2 Moderator7 Dec 2025#71
s.roos, post #51: post #50 answers the question as asked. The question underneath it is different. What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint. Go to post

This follows post #68 rather than contradicting it.

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

1 like in reply to #51 8mo
TP
tracked_parcelTL27 Dec 2025#72
NI
n.ibarraTL2 Moderator7 Dec 2025#73

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

15 likes 8mo
KO
k.otieno_statsTL3Statistician7 Dec 2025#74
MJayawardena, post #37: Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

30 likes in reply to #37 8mo
ZO
z.okonkwoTL2 Moderator7 Dec 2025#75

Picking up post #72: that is the part I would want checked first.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

0 likes 8mo
SS
system_suitabilityTL3Analytical chemist7 Dec 2025#76

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

3 likes 8mo
JA
j.asanteTL2 Moderator8 Dec 2025 · edited#77

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

10 likes 8mo
PI
p.iyer_pharmdTL3Pharmacist8 Dec 2025#78
f.chowdhury, post #47: How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint. Go to post

On post #74 — agreed on the reasoning, with one qualification.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

22 likes in reply to #47 8mo
AV
ai.vukovicTL2 Moderator8 Dec 2025#79

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

5 likes 8mo
W
WendelboeTL2Member8 Dec 2025#80

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

14 likes 8mo
DO
d.oyelaranTL3Pharmacist8 Dec 2025#81
s.oyelaran, post #38: Worth separating two things that post #34 runs together. Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a… Go to post

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

5 likes in reply to #38 8mo
CT
c.tullochTL2 Moderator8 Dec 2025#82

Picking up post #79: that is the part I would want checked first.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

0 likes 8mo
K
KLindqvistTL4 Moderator8 Dec 2025#83
Staff post. Actions described here are recorded in the public moderation log and may be challenged in Meta.

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

28 likes 8mo
AI
a.ibarraTL2 Moderator8 Dec 2025 · edited#84

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

14 likes 8mo
LW
l.wikstromTL2 Moderator8 Dec 2025#85
r.coelho, post #32: Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting. Go to post

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

2 likes in reply to #32 8mo
VN
v.nascimentoTL2 Moderator8 Dec 2025#86
o.vogel, post #13: Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently. Go to post

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes in reply to #13 8mo
NR
n.rahimiTL2 Moderator9 Dec 2025#87

Worth separating two things that post #83 runs together.

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

21 likes 8mo
PA
p.amankwahTL2 Moderator9 Dec 2025#88

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

9 likes 8mo
TY
two_year_lineTL3Regular9 Dec 2025 · edited#89

Coming back to post #87, because the follow-up matters more than the original answer.

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

13 likes 8mo
SK
s.kuuselaTL2 Moderator9 Dec 2025#90
dexa_twice_yearly, post #4: Picking up the opening post: that is the part I would want checked first. Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up. Go to post

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

4 likes in reply to #4 8mo