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Evidence · Preprints · continued

Tracking a preprint to publication: a worked example posts 121–148

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

J
JFitzgibbonTL2Member12 Dec 2025#121

This follows post #118 rather than contradicting it.

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

13 likes 8mo
NN
n.nakamuraTL2 Moderator12 Dec 2025#122
m.ndiaye, post #67: Coming back to post #65, because the follow-up matters more than the original answer. Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

I read post #120 twice before replying, because I had assumed the opposite.

Two things before anyone answers the substance.

First, the context in the first post is clear and specific. Second, the question is framed so that an answer can actually address it. Both are the norm here and both matter more than they sound.

28 likes in reply to #67 8mo
GH
g.haalandTL3Regular12 Dec 2025#123

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

0 likes 8mo
SB
s.beaulieuTL2 Moderator12 Dec 2025#124

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

5 likes 8mo
SD
s.duarteTL212 Dec 2025#125
VB
v.bhattacharyaTL2 Moderator12 Dec 2025#126
Leiterman, post #56: Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim. Go to post

Coming back to post #124, because the follow-up matters more than the original answer.

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

0 likes in reply to #56 8mo
AS
a.salcedoTL3Regular12 Dec 2025#127

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

2 likes 7mo
AS
a.sorensenTL2 Moderator13 Dec 2025#128

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

8 likes 7mo
BP
bench_peakTL3Regular13 Dec 2025#129

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

5 likes 7mo
SO
s.oyelaranTL2 Moderator13 Dec 2025#130

Unrefereed work is not worthless. A great deal of it survives review substantially unchanged. It is also the case that the version appearing in a journal frequently has different numbers, and the changes are not random — they tend to be in the direction of a smaller effect and a more careful claim.

14 likes 7mo
DB
d.barrosTL2 Moderator13 Dec 2025#131

Worth separating two things that post #127 runs together.

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

8 likes 7mo
MI
m.ivaturiTL2 Moderator13 Dec 2025#132

post #131 is right about the mechanism and I think understates the practical bit.

Thank you for the correction. I have edited my earlier post with a note rather than silently, so the thread still makes sense to read. The error was mine and it was the kind that comes from remembering a figure instead of looking it up.

2 likes 7mo
CA
c.adebayoTL2 Moderator13 Dec 2025#133
a.frisk, post #99: Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised. Go to post

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

0 likes in reply to #99 7mo
HK
h.karlsenTL2 Moderator13 Dec 2025 · edited#134
outline_first, post #70: Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real. Go to post

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

19 likes in reply to #70 7mo
SF
s.ferreiraTL2 Moderator13 Dec 2025#135

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

4 likes 7mo
CN
c.niemelTL3Regular13 Dec 2025#136

post #135 answers the question as asked. The question underneath it is different.

Always label it as a preprint in any discussion. A preprint is not a published trial and it is not settled knowledge. Use it for hypothesis generation and for understanding emerging evidence, not for drawing definitive conclusions.

0 likes 7mo
NV
n.vogelTL2 Moderator13 Dec 2025#137

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

27 likes 7mo
OC
o.cousineauTL3Regular13 Dec 2025#138
BBramley, post #58: I read post #56 twice before replying, because I had assumed the opposite. How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint. Go to post

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

13 likes in reply to #58 7mo
RC
r.chukwuTL2 Moderator14 Dec 2025 · edited#139

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

18 likes 7mo
T
TavaresTL1Member14 Dec 2025#140

Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists.

7 likes 7mo
RJ
r.jhannsdttirTL3Regular14 Dec 2025#141

Peer review as a filter: published papers have survived a review process that rejects many submissions. Preprints have not. Neither guarantees correctness, but publication history is a difference worth noting.

10 likes 7mo
AV
a.vermeulenTL2 Moderator14 Dec 2025#142
r.molnar, post #41: I read post #39 twice before replying, because I had assumed the opposite. Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint.

23 likes in reply to #41 7mo
TK
t.kulkarniTL3Regular14 Dec 2025 · edited#143

Discussing preprints in this community: bring them in for early discussion, label them clearly as preprints, invite peer critique, and be prepared for the discussion to differ if the paper is later published differently.

0 likes 7mo
GO
g.oyelaranTL2 Moderator14 Dec 2025#144

I read post #142 twice before replying, because I had assumed the opposite.

Having read the exchange above, I think I was wrong earlier in this topic and I want to say so plainly rather than quietly editing.

The correction was fair and I had been repeating something I had not checked carefully enough.

1 like 7mo
HA
h.almeidaTL2Member14 Dec 2025#145

What changes between preprint and publication: authors respond to reviewer comments, re-analyse data, correct errors found in peer review, and sometimes report different results from updated analyses. The published version is not the same as the preprint.

6 likes 7mo
JP
j.palaciosTL2 Moderator14 Dec 2025#146
BBramley, post #58: I read post #56 twice before replying, because I had assumed the opposite. How to cite a preprint: author last name, first initial, et al. Title. Server name [preprint]. Posted date. Doi. Include the server name and note that it is a preprint. Go to post

Server repositories: medRxiv for medicine, bioRxiv for biology. Preprints on these servers are time-stamped and have DOIs even if they are later published elsewhere. Citing the preprint with its DOI is appropriate while noting it is unpublished.

16 likes in reply to #58 7mo
B
BDraganovTL2Member14 Dec 2025#147
r.zielinski, post #106: Check whether it was later published: searching for the preprint's first author and keywords in PubMed might find a published version. The published version is the stronger citation if it exists. Go to post

Picking up post #144: that is the part I would want checked first.

Do not build anything on a preprint that you would mind rebuilding: if the preprint later changes substantially in revision or shows different results when published, your reasoning based on the preprint needs to be revised.

32 likes in reply to #106 7mo
HK
h.kimaniTL2 Moderator14 Dec 2025#148

Coming back to post #146, because the follow-up matters more than the original answer.

Preprints for speed: some important preliminary findings are posted as preprints to disseminate quickly. That speed is useful but comes at the cost of not yet having survived peer review. The trade-off is real.

0 likes 7mo

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