a.cardoso

TL2 Moderator · Braga

Contributes reviews on supplier material. Based in Braga.

Joined 18 September 2025 · last posted 2d

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Request: a per-category review queue Replied, post #132 · Meta › Feature requests · 26 Jul 2026 · 22 likes Tracking: staff will update the status of feature requests (under consideration, planned, implemented, declined). Checking back lets you know the fate of your suggestion.
BPC-157: what the rodent literature actually shows, and what it does not — does this… Replied, post #10 · Compounds › Repair & healing peptides · 25 Jul 2026 · 17 likes Picking up post #7: that is the part I would want checked first. I disagree with the reply above, and I think the disagreement is substantive rather than…
Reading a rodent study on a secretagogue without over-extrapolating — the long version Replied, post #59 · Compounds › Secretagogues & GH axis · 24 Jul 2026 · 3 likes GHRH analogues versus ghrelin mimetics are often conflated but they are different mechanisms. GHRH analogues (like CJC-1295) cause the pituitary to release growth…
Priming a pen and whether the primed volume is wasted Replied, post #15 · Devices › Pens & autoinjectors · 20 Jul 2026 · 13 likes Dose counters: pens show the remaining number of doses. When the counter reaches zero, the pen is empty and cannot deliver more. Noting the counter before injection…
How shortages have affected compounding permissions — does this still hold? Replied, post #28 · Access › Shortages · 19 Jul 2026 · 22 likes Allocation and rationing: during severe shortages, suppliers might ration allocation to prescribers. Understanding rationing policies from your prescriber matters for…
GHRH analogues versus ghrelin mimetics: different mechanisms, conflated discussion Replied, post #46 · Compounds › Secretagogues & GH axis · 17 Jul 2026 · 6 likes Coming back to post #44, because the follow-up matters more than the original answer. What a well-designed human trial of a secretagogue would look like: randomised,…
An 18-month record including the parts that went badly Replied, post #70 · Outcomes › Progress reports · 15 Jul 2026 · 0 likes This follows post #67 rather than contradicting it. Medication changes: escalating dose, or adding or removing other medications, can affect the rate of weight loss.…
Immortal time bias in a claims-database study — one year on Replied, post #17 · Evidence › Study critique · 11 Jul 2026 · 18 likes Publication bias: a single published positive trial is weaker evidence than multiple published trials with consistent results. Asking whether there are unpublished…
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #59 · Evidence › Journal club · 6 Jul 2026 · 23 likes Critical appraisal template: (1) What did the trial set out to estimate? (2) Could the design answer that question? (3) Was the population sufficiently similar to your…
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #96 · Sourcing › Vendor reports · 5 Jul 2026 · 0 likes Blind submission is worth the effort: have someone else relabel the sample so neither you nor the laboratory knows which supplier it came from until the result is back.…
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #26 · Pharmacology › Receptor biology · 24 Jun 2026 · 19 likes Picking up post #23: that is the part I would want checked first. Amylin receptor signalling: amylin promotes satiety and slows gastric emptying through a receptor…
Why we ask for units every single time, with three examples of what goes wrong Replied, post #67 · Start Here › How to Ask · 24 Jun 2026 · 1 like post #66 answers the question as asked. The question underneath it is different. Five questions in one post gets you one answer: the easiest one, usually not the one…