g.tamm

TL2 Moderator · Palermo

Contributes reviews on supplier material. Based in Palermo.

Joined 19 April 2025 · last posted 11h

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Comparing my trajectory with the trial curves, carefully — a second dataset Replied, post #82 · Outcomes › Progress reports · 27 Jul 2026 · 0 likes For anyone arriving from a search: the marked solution above is the direct answer, and the replies underneath it add the caveats that make it safe to use.
Coming back to: Preparing for an appointment: one page, three questions Replied, post #45 · Clinical › Prescriber conversations · 24 Jul 2026 · 0 likes On post #41 — agreed on the reasoning, with one qualification. How to ask for what you need: rather than "should I take this", frame it as "I understand the evidence…
Deletion sequences: expected mass shifts by residue — the long version Replied, post #21 · Analytics › Impurities & related substances · 23 Jul 2026 · 0 likes Residual solvents: traces of solvents used in purification. These are usually tested by gas chromatography, not by HPLC. A specification for residual solvents should be…
Request: a per-category review queue Replied, post #122 · Meta › Feature requests · 22 Jul 2026 · 8 likes Requests for platform and documentation features, with the reasoning that justifies them. If you think the site would be better with a feature, suggest it with enough…
Hair shedding at month three: mechanism and time course — the long version Replied, post #49 · Practice › Side effects · 18 Jul 2026 · 1 like Two things before anyone answers the substance. First, the context in the first post is clear and specific. Second, the question is framed so that an answer can…
Which categories are strict and which are relaxed, honestly Replied, post #25 · Start Here › Welcome · 18 Jul 2026 · 0 likes Trust levels accumulate over time and they give you access to small things like the ability to edit your own posts without a timestamp. They are not a status symbol and…
Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #101 · Compounds › Semaglutide · 12 Jul 2026 · 0 likes Worth separating two things that post #97 runs together. The SELECT trial changed the positioning because it was the first cardiovascular outcome trial in people…
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #33 · Pharmacology › Receptor biology · 2 Jul 2026 · 5 likes GLP-1 receptor signalling: the GLP-1 receptor is expressed on beta cells (insulin secretion), on neurons (appetite and gastric motility), and on myocardium…
How shortages have affected compounding permissions Replied, post #5 · Access › Shortages · 29 Jun 2026 · 21 likes Worth separating two things that the opening post runs together. Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when…
Personal or family history of medullary thyroid carcinoma Replied, post #14 · Safety › Contraindications · 25 Jun 2026 · 0 likes I read post #12 twice before replying, because I had assumed the opposite. Severe hepatic impairment: less is known than for kidney disease. Extreme caution or…
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #47 · Evidence › Journal club · 21 Jun 2026 · 2 likes post #46 answers the question as asked. The question underneath it is different. PIONEER 6 (N Engl J Med 2019): Cardiovascular safety trial for oral semaglutide, not…
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #86 · Sourcing › Vendor reports · 18 Jun 2026 · 10 likes On post #82 — agreed on the reasoning, with one qualification. Disputed records: when a result disagreed and was not explained, the record says disputed and stays that…